Investigating the Effect of Ocrelizumab in African Americans and Caucasians With Relapsing Multiple Sclerosis

Part of paid clinical trials in Detroit, Michigan.

Sponsor
Wayne State University
Study ID
NCT04458688
Status
Recruiting
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Conditions

  • Multiple Sclerosis, Relapsing-Remitting

Eligibility Criteria

Sex
ALL
Age
18 Years - 60 Years
Healthy Volunteers
Not accepted

Interventions

  • Observation of Ocrelizumab as Treatment in RRMS Patients — OTHER
    It is decided by the patient and their physician to begin taking ocrelizumab PRIOR to study enrollment. The study is only observing the effects of ocrelizumab as a pre-decided treatment option for a patient's MS.

Study Details

The investigators intend to examine the effects of ocrelizumab use in African American multiple sclerosis disease course compared to Caucasian disease course utilizing imaging measures with magnetic resonance imaging (MRI) and optical coherence tomography angiography (OCT-A)..

Key Dates

Start date
Nov 20, 2021
Status verified
Jun 2022
Primary completion
Jul 31, 2025
Completion
Dec 31, 2030

Study Design

Enrollment
80 participants (estimated)

Arms

  • Arm: African Americans with RRMS
    Participants who are diagnosed with relapsing multiple sclerosis and who have chosen to start or recently started using ocrelizumab as their disease modifying therapy. Age range: 18 to 60 years old. Ethnicity: Self-described as African American.
  • Arm: Caucasian American with RRMS
    Participants who are diagnosed with relapsing multiple sclerosis and who have chosen to start or recently started using ocrelizumab as their disease modifying therapy. Age range: 18 to 60 years old. Ethnicity: Self-described as Caucasian American.

Primary Outcome Measure

Magnetic Resonance Imaging (MRI) with contrast [ Time Frame: Change in MRI at BL, Month 6, Month 12, and Month 24 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Wayne State UniversityDetroitMichigan48201
Zahid Latif
[email protected]
313-966-0473
Kelly Jia
[email protected]
313-966-9407

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By research site
Wayne State University· Detroit, MI

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