Spermatogonial Stem Cell (SSC) Transplant and Testicular Tissue Grafting

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
University of Pittsburgh
Study ID
NCT04452305
Status
Recruiting
Apply to this trial

Conditions

  • Autoimmune Disorder
  • Cancer
  • Infertility, Male

Eligibility Criteria

Sex
MALE
Age
N/A - N/A
Healthy Volunteers
Not accepted

Interventions

  • Spermatogonial Stem Cell Transplant and Testicular Tissue Grafting — PROCEDURE
    Spermatogonial stem cell transplant and testicular tissue grafting is performed to produce sperm.

Study Details

Spermatogonial stem cell transplantation through ultrasound guided rete testis injection and testicular tissue grafting will be performed for participants who have frozen testicular tissue prior to gonadotoxic therapy. The purpose of this study is to test the safety and feasibility of these transplant technologies and restore fertility for these participants.

Key Dates

Start date
Nov 10, 2023
Status verified
Apr 2026
Primary completion
Dec 28, 2029
Completion
May 31, 2030

Study Design

Enrollment
10 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Spermatogonial Stem Cell Transplant & Testicular Tissue Graft
    Stem cell transplantation Testicular tissue grafting

Primary Outcome Measure

Number of participants with return of spermatogenesis [ Time Frame: 3 months-1year ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Magee-Womens HospitalPittsburghPennsylvania15213
Rachel Neelley
[email protected]
412-641-7475

Find similar trials in Pittsburgh, PA

By research site
Magee-Womens Hospital· Pittsburgh, PA

Related Studies