The Olmsted NAFLD Epidemiology Study (TONES)

Part of paid clinical trials in Rochester, Minnesota.

Sponsor
Mayo Clinic
Study ID
NCT04365855
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Magnetic Resonance Elastography — DIAGNOSTIC_TEST
    Combines MRI imaging with sound waves to create a visual map (elastogram) showing the stiffness of body tissues.
  • Blood draw — OTHER
    Clinical blood tests with a focus on liver function parameters and diabetes
  • Liver biopsy — PROCEDURE
    If indicated per MRE results a biopsy will be taken of the liver.
  • Fibro Scan — PROCEDURE
    If indicated per MRE results a fibroscan will be performed of the liver.

Study Details

Researchers are assessing the prevalence of Non-alcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) in the population and assembling a well-characterized cohort of adults with NAFLD and NASH to validate models of NAFLD diagnosis and determine long-term outcomes.

Key Dates

Start date
Oct 10, 2020
Status verified
Jan 2026
Primary completion
Jun 30, 2028
Completion
Jun 30, 2028

Study Design

Enrollment
800 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC

Arms

  • Other: Subjects at risk for NAFLD
    Adult Olmsted County residents identified as at risk for NAFLD will receive Magnetic Resonance Imaging (MRE,) blood tests,and possible biopsy.

Primary Outcome Measure

Prevalence of NAFLD and NASH in the population [ Time Frame: 5 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo Clinic in RochesterRochesterMinnesota55905-

Find similar trials in Rochester, MN

By research site
Mayo Clinic in Rochester· Rochester, MN

Related Studies