Study of Circulating Monocytes in Patients With Ischemic Vascular Disease

Part of paid clinical trials in Farmington, Connecticut.

Sponsor
UConn Health
Study ID
NCT04321512
Status
Recruiting
Apply to this trial

Conditions

  • Ischemia
  • Myocardial Infarction
  • Stroke, Ischemic

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • There is no intervention given to the subjects — OTHER
    Not appicable

Study Details

The purpose of this research study is to discover the functions of circulating white blood cells, called monocytes, and associated circulating substances in heart attack and ischemic stroke patients. Ischemic Strokes (clots) occur as a result of an obstruction within a blood vessel supplying blood to the brain. A type of monocyte carrying a surface marker called "P2X4" helps the immune system sense and respond to danger signals from the body such as heart muscle and brain tissue injuries. The researchers expect to learn more about how these monocyte cells react to heart and brain tissue injury, and how the cells may then produce proteins or other chemical substances which promote the healing of heart muscle after heart attack and brain tissue after an ischemic stroke.

Key Dates

Start date
Dec 1, 2013
Status verified
Jul 2025
Primary completion
Dec 1, 2027
Completion
Dec 1, 2027

Study Design

Enrollment
300 participants (estimated)

Primary Outcome Measure

Hospitalization for Myocardial Infarction, Stroke, or death [ Time Frame: 3 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Connecticut Health CenterFarmingtonConnecticut06030
Michelle Izydorczak, BA,MA
[email protected]
860-679-7549
Bruce Liang, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Farmington, CT

By research site
University of Connecticut Health Center· Farmington, CT

Related Studies