Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity

Part of paid clinical trials in Scottsdale, Arizona.

Sponsor
Mayo Clinic
Study ID
NCT04232566
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
30 Years - 70 Years
Healthy Volunteers
Accepted

Interventions

  • Bariatric surgery — PROCEDURE
    Evaluate liver fibrosis by elastography before gastric bypass surgery.

Study Details

This study is being done to better understand the relationship between inflammation in adipose tissue (AT), abnormal deposition of fat around the liver and how this affects its appearance and function and ultimately insulin resistance.

Key Dates

Start date
Feb 20, 2022
Status verified
Jan 2026
Primary completion
Dec 31, 2025
Completion
Dec 30, 2027

Study Design

Enrollment
60 participants (estimated)

Arms

  • Arm: Weight loss surgery
    Gastric bypass surgery will be followed by weight loss as standard of care. Liver fibrosis by elastography will be determined before surgery.

Primary Outcome Measure

Liver fibrosis [ Time Frame: Baseline ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo Clinic in ArizonaScottsdaleArizona85259
Stewart Keegan
[email protected]
480-301-4164
Elena De Filippis, MD,PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Scottsdale, AZ

By condition
Obesity / overweight
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
Mayo Clinic in Arizona· Scottsdale, AZ

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