Non-Invasive Quantification of Liver Health in NASH (N-QUAN)

Part of paid clinical trials in Chandler, Arizona.

Sponsor
Perspectum
Study ID
NCT04054310
Status
Recruiting
Apply to this trial

Conditions

  • NASH - Nonalcoholic Steatohepatitis

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Liver Multi Scan — DIAGNOSTIC_TEST
    MRI to create cT1, T2\* and PDFF images of patients liver.

Study Details

To evaluate, in patients with suspected NASH referred for liver biopsy, the diagnostic performance of CT1 at discriminating those with NAS≥4 \& F≥2 from those without.

Key Dates

Start date
Aug 5, 2020
Status verified
May 2026
Primary completion
Jun 1, 2026
Completion
Jun 1, 2026

Study Design

Enrollment
225 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC

Arms

  • Experimental: Study-gate
    Single arm of biopsy naïve participants suspected of having NAFLD or NASH, who have been referred for a liver biopsy as part of routine clinical care

Primary Outcome Measure

Diagnostic performance of cT1 [ Time Frame: 12 months ]

Central Contacts

Locations (7)

FacilityCityStateZIPSite coordinators
Arizona Liver HealthChandlerArizona85224
David Rios, MD
[email protected]
Naim Alkhouri, MD (PRINCIPAL_INVESTIGATOR)
RUSH University Medical CenterChicagoIllinois60612
Lelani Fetrow, BSN
[email protected]
Nancy Reau, MD (PRINCIPAL_INVESTIGATOR)
Indiana University HealthIndianapolisIndiana46202
Sreemala Murthy, BSc
[email protected]
Raj Vuppalanchi, MD (PRINCIPAL_INVESTIGATOR)
Icahn School of Medicine at Mount SinaiNew YorkNew York10029
Elianna Sanchez
[email protected]
Douglas Dieterich (PRINCIPAL_INVESTIGATOR)
Liver Center of TexasDallasTexas75234-
University of VirginiaCharlottesvilleVirginia22908
Cheree Denbee
[email protected]
Zachary Henry (PRINCIPAL_INVESTIGATOR)
Virginia Common wealth UniversityRichmondVirginia23284
Arun Sanyal, MD
[email protected]
8048284060
Rebecca Collen, BSC
[email protected]
8048280100
Arun Sanyal (PRINCIPAL_INVESTIGATOR)

Find similar trials in Chandler, AZ

By research site
Arizona Liver Health· Chandler, AZRUSH University Medical Center· Chicago, ILIndiana University Health· Indianapolis, INIcahn School of Medicine at Mount Sinai· New York, NYLiver Center of Texas· Dallas, TXUniversity of Virginia· Charlottesville, VA

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