EsophaCap for the Detection of Early Esophageal Carcinoma

Part of paid clinical trials in Baltimore, Maryland.

Sponsor
Johns Hopkins University
Study ID
NCT04214119
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Study Details

This study is to identify potential biomarkers for the early detection of Barrett's Esophagus, esophageal carcinoma (both adenocarcinoma and squamous cell carcinoma), and gastric cancer via sponge cytology.

Key Dates

Start date
Jan 12, 2016
Status verified
Dec 2025
Primary completion
Dec 19, 2028
Completion
Dec 19, 2028

Study Design

Enrollment
2,500 participants (estimated)

Arms

  • Arm: Control
    Patients age 18 or greater who have undergone esophagogastroduodenoscopy and does not have a diagnosis of Barrett's esophagus or esophageal/gastric malignancy.
  • Arm: Barrett's esophagus
    Patients age 18 or greater who have undergone esophagogastroduodenoscopy and diagnosed with Barrett's esophagus via pathology.
  • Arm: Esophageal carcinoma
    Patients age 18 or greater who have diagnosis of primary esophageal carcinoma.
  • Arm: Gastric cancer
    Patients age 18 or greater who have diagnosis of primary esophageal cancer.

Primary Outcome Measure

Difference in methylation of gene markers to discriminate Barrett's esophagus from non-pathological esophageal squamous and gastric cardia tissue. [ Time Frame: 1 day ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
Bayview Medical CenterBaltimoreMaryland21205
Stephen J Meltzer, M.D.
[email protected]
410-502-6071
Johns Hopkins HospitalBaltimoreMaryland21205
Stephen Meltzer, M.D.
[email protected]
410-502-6071

Find similar trials in Baltimore, MD

By condition
Esophageal cancerGastric cancer
By specialty
OncologyGI oncology
By research site
Bayview Medical Center· Baltimore, MDJohns Hopkins Hospital· Baltimore, MD

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