Study of Individuals Affected With Hypoplasminogenemia
Part of paid clinical trials in Birmingham, Alabama.
- Sponsor
- Indiana Hemophilia &Thrombosis Center, Inc.
- Study ID
- NCT03797495
- Status
- Recruiting
Conditions
- Plasminogen Deficiency
Eligibility Criteria
- Sex
- ALL
- Age
- N/A - N/A
- Healthy Volunteers
- Not accepted
Study Details
This is an Investigator initiated retrospective and prospective single cohort study. The study will utilize an international registry and develop a specimen biobank to provide an improved understanding of the natural history of hyposplasminogenemia, to elucidate the heterogeneity of phenotypic expression, identify markers to predict disease course, and inform improved therapeutic modalities
Key Dates
- Start date
- Dec 18, 2018
- Status verified
- Mar 2026
- Primary completion
- Jun 29, 2029
- Completion
- Nov 26, 2029
Study Design
- Enrollment
- 100 participants (estimated)
Primary Outcome Measure
Define the natural history of plasminogen deficiency [ Time Frame: 2 years ]
Central Contacts
- Amy D Shapiro, MD317-871-0000
- Charles Nakar, MD317-871-0000
Locations (13)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| The University of Alabama (UAB) | Birmingham | Alabama | 35233 | Sharon Davis Christina Bemrich-Stolz, MD (PRINCIPAL_INVESTIGATOR) |
| Rush University Medical Center | Chicago | Illinois | 60612 | Mindy Simpson, MD (PRINCIPAL_INVESTIGATOR) |
| Indiana Hemophila @Thrombosis Center | Indianapolis | Indiana | 46260 | Amy D Shapiro, MD (PRINCIPAL_INVESTIGATOR) Charles Nakar, MD (SUB_INVESTIGATOR) |
| University of Minnesota, Pediatric Hem/Onc & Cancer Survivorship Program | Minneapolis | Minnesota | 55455 | Alex Boucher, MD (PRINCIPAL_INVESTIGATOR) |
| Stony Brook University | Stony Brook Medicine | East Setauket | New York | 11733 | Nicole Muhlbauer, MD (PRINCIPAL_INVESTIGATOR) |
| SUNY Upstate Medical University, Pediatric Hematology/Oncology | Syracuse | New York | 13210 | Andrea Dvorak, MD (PRINCIPAL_INVESTIGATOR) |
| University of North Carolina at Chapel Hill | Raleigh | North Carolina | 27599 | Brett Phillips, MA Yasmina Abajas, MD (PRINCIPAL_INVESTIGATOR) |
| Wake Forest University | Winston-Salem | North Carolina | 27157 | Amanda Blair, MD (PRINCIPAL_INVESTIGATOR) |
| Hemophilia Center of Western Pennsylvania | Pittsburgh | Pennsylvania | 15213 | |
| Vanderbilt Children's Hematology-Oncology | Nashville | Tennessee | 37232 | - |
| Cook Children's Medical Center | Forth Worth | Texas | 76104 | Marcela Torres, MD (PRINCIPAL_INVESTIGATOR) |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | - |
| Seattle Children's Hospital | Seattle | Washington | 98105-3901 | Gavin Roach, MD (PRINCIPAL_INVESTIGATOR) |
Find similar trials in Birmingham, AL
By research site
The University of Alabama (UAB)· Birmingham, ALRush University Medical Center· Chicago, ILIndiana Hemophila @Thrombosis Center· Indianapolis, INUniversity of Minnesota, Pediatric Hem/Onc & Cancer Survivorship Program· Minneapolis, MNStony Brook University | Stony Brook Medicine· East Setauket, NYSUNY Upstate Medical University, Pediatric Hematology/Oncology· Syracuse, NY