Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid Nodules

Part of paid clinical trials in Duarte, California.

Sponsor
City of Hope Medical Center
Study ID
NCT03676647
Status
Recruiting
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Conditions

  • Thyroid Gland Nodule

Eligibility Criteria

Sex
ALL
Age
19 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Diagnostic DNA Methylation Signature — OTHER
    Undergo collection of tissue samples

Study Details

This trial studies how well the diagnostic deoxyribonucleic acid (DNA) methylation signature works in detecting thyroid cancer in patients with thyroid nodules. Using diagnostic testing, such as the diagnostic DNA methylation signature, may be a less invasive way to check for thyroid cancer.

Key Dates

Start date
Jan 1, 2027
Status verified
Jun 2026
Primary completion
Sep 25, 2028
Completion
Sep 25, 2028

Study Design

Enrollment
22 participants (estimated)

Arms

  • Arm: Diagnostic (biospecimen collection)
    Previously collected FNA aspiration specimen samples are analyzed via DDMS assay. Participants undergo FNA aspiration for collection of tissue samples for analysis via DDMS assay.

Primary Outcome Measure

Sensitivity of the diagnostic deoxyribonucleic acid (DNA) methylation signature (DDMS) [ Time Frame: Up to 5 years ]

Locations (1)

FacilityCityStateZIPSite coordinators
City of Hope Medical CenterDuarteCalifornia91010
Maria Hahn, PhD
[email protected]
626-256-4673
Maria Hahn (PRINCIPAL_INVESTIGATOR)

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By research site
City of Hope Medical Center· Duarte, CA

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