Efficacy and Safety of Tofacitinib in Subjects With Active Ankylosing Spondylitis (AS)

Part of paid clinical trials in Huntsville, Alabama.

Sponsor
Pfizer
Study ID
NCT03502616
Phase
PHASE3
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

The purpose of this study is to determine if tofacitinib is safe and effective in subjects with active ankylosing spondylitis.

Key Dates

Start date
Jun 7, 2018
Status verified
Aug 2021
Primary completion
Dec 19, 2019
Completion
Aug 20, 2020

Study Design

Enrollment
270 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Tofacitinib
  • Placebo Comparator: Placebo

Primary Outcome Measure

Percentage of Participants Achieving Assessment of SpondyloArthritis International Society (ASAS)20 Response at Week 16 [ Time Frame: Week 16 ]

Locations (28)

FacilityCityStateZIPSite coordinators
Rheumatology Associates of North Alabama, PCHuntsvilleAlabama35801-
Arizona Arthritis & Rheumatology Associates, P.C.GilbertArizona85297-
Medvin Clinical ResearchCovinaCalifornia91722-
Rheumatology Center of San Diego PCSan DiegoCalifornia92128-
University of California, San Francisco Medical CenterSan FranciscoCalifornia94143-
Robin K. Dore, MD, Inc.TustinCalifornia92780-
New England Research Associates, LLCBridgeportConnecticut06606-
Advanced RadiologyStamfordConnecticut06902-
Stamford Therapeutics ConsortiumStamfordConnecticut06905-
Southcoast Research Center, Inc.MiamiFlorida33136-
Millennium ResearchOrmond BeachFlorida32174-
Bluegrass Community Research, IncLexingtonKentucky40504-
Center for Rheumatology and Bone ResearchWheatonMaryland20902-
M3-Emerging Medical Research, LLCDurhamNorth Carolina27704-
Paramount Medical Research and Consulting, LLCMiddleburg HeightsOhio44130-
Oregon Health & Science UniversityPortlandOregon97239-
Altoona Center For Clinical ResearchDuncansvillePennsylvania16635-
Articularis Healthcare Group, Inc d/b/a Low Country RheumatologySummervilleSouth Carolina29486-
Precision Comprehensive Clinical Research SolutionsColleyvilleTexas76034-
Adriana Pop-Moody MD - Clinic PACorpus ChristiTexas78404-
Metroplex Clinical Research CenterDallasTexas75231-
Clinical Research UnitHoustonTexas77030-
Investigational Drug ServicesHoustonTexas77030-
Memorial Hermann Hospital ImagingHoustonTexas77030-
Southwest Rheumatology Research LLCMesquiteTexas75150-
Trinity Universal Research Associates, Inc.PlanoTexas75024-
Advanced Rheumatology of HoustonThe WoodlandsTexas77382-
Arthritis Northwest, PLLCSpokaneWashington99204-

Find similar trials in Huntsville, AL

By research site
Rheumatology Associates of North Alabama, PC· Huntsville, ALArizona Arthritis & Rheumatology Associates, P.C.· Gilbert, AZMedvin Clinical Research· Covina, CARheumatology Center of San Diego PC· San Diego, CAUniversity of California, San Francisco Medical Center· San Francisco, CARobin K. Dore, MD, Inc.· Tustin, CA

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