Effect of Liraglutide on Neural Responses to High Fructose Corn Syrup in Individuals With Obesity.

Part of paid clinical trials in New Haven, Connecticut.

Sponsor
Yale University
Study ID
NCT03500484
Phase
EARLY_PHASE1
Status
Terminated

Conditions

  • Neural Development
  • Obesity, Childhood

Eligibility Criteria

Sex
ALL
Age
18 Years - 39 Years
Healthy Volunteers
Accepted

Interventions

  • Liraglutide — DRUG
    Liraglutide will be supplied in the following package sizes containing disposable, pre-filled, multidose pens. Each individual pen delivers doses of 0.6 mg, 1.2 mg, 1.8 mg, 2.4 mg or 3 mg (6 mg/mL, 3 mL). Liraglutide will be self-administered daily for 12 weeks under the following regimen: 0.6mg for 1 week, 1.2mg for 1 week, 1.8mg for 1 week, 2.4mg for 1 week, 3.0mg until week 12.

Study Details

To study the effects of liraglutide on neural responses to high fructose corn syrup (HFCS) in individuals with obesity.

Key Dates

Start date
Jun 6, 2018
Status verified
Jul 2024
Primary completion
Jun 25, 2020
Completion
Jun 25, 2020

Study Design

Enrollment
13 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: obese subjects
    Subjects will self-administer Liraglutide once daily for 12 weeks.
  • No Intervention: lean subjects
    no intervention

Primary Outcome Measure

Brain Response in Obese Young Adults Who Drink Sugar Sweetened Beverages. [ Time Frame: 1 week ]

Locations (1)

FacilityCityStateZIPSite coordinators
Yale UniversityNew HavenConnecticut06511-

Find similar trials in New Haven, CT

By research site
Yale University· New Haven, CT

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