Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Boston Children's Hospital
Study ID
NCT03059420
Status
Recruiting
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Conditions

  • Athabaskan Brainstem Dysgenesis
  • Brown Syndrome
  • Congenital Fibrosis of Extraocular Muscles
  • Duane Radial Ray Syndrome
  • Duane Retraction Syndrome
  • Eleventh Nerve Disorder
  • Facial Palsy
  • Facial Paresis, Hereditary, Congenital
  • Fifth Nerve Palsy
  • Fourth Nerve Palsy
  • Horizontal Gaze Palsy
  • Horizontal Gaze Palsy With Progressive Scoliosis
  • Levator-Medial Rectus Synkinesis
  • Marcus Gunn Syndrome
  • Mobius Syndrome
  • Moebius Sequence
  • Ninth Nerve Disorder
  • Ocular Motility Disorders
  • Seventh Nerve Palsy
  • Sixth Nerve Palsy
  • Strabismus Congenital
  • Synkinesis
  • Third Nerve Palsy
  • Tongue Paralysis
  • Twelfth Nerve Disorder
  • Vagus Nerve Paralysis

Eligibility Criteria

Sex
ALL
Age
1 Day - N/A
Healthy Volunteers
Accepted

Study Details

The purpose of this study is to identify genes associated with impaired development and function of the cranial nerves and brainstem, which may result in misalignment of the eyes (strabismus) and related conditions.

Key Dates

Start date
Feb 1, 2004
Status verified
Feb 2026
Primary completion
Jan 31, 2030
Completion
Jan 31, 2030

Study Design

Enrollment
20,000 participants (estimated)

Primary Outcome Measure

Identifying and characterizing genes important in normal development and function of the ocular motility system, cranial nerves and brainstem and associated with congenital cranial dysinnervation disorders and related anomalies. [ Time Frame: Ongoing ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Boston Children's HospitalBostonMassachusetts02115-

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By research site
Boston Children's Hospital· Boston, MA

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