Prospective Investigation of Multiple Sclerosis in the Three Rivers Region

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
University of Pittsburgh
Study ID
NCT02994121
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
7 Years - N/A
Healthy Volunteers
Accepted

Study Details

In this longitudinal prospective natural history study of multiple sclerosis (MS), the overarching goal is to understand the factors that influence individual variation in disease trajectory and treatment response and pave the way for realizing precision medicine in MS. Because MS is a chronic neurological disorder, this observational cohort study will span a 30-year time frame.

Key Dates

Start date
Dec 31, 2016
Status verified
Dec 2025
Primary completion
Jan 31, 2047
Completion
Jan 31, 2047

Study Design

Enrollment
7,500 participants (estimated)

Arms

  • Arm: People with Multiple Sclerosis or Related Disorders
    Individuals must be 7 years or older, diagnosed with multiple sclerosis or related disorders, including a first central nervous system demyelinating episode with a positive MRI scan or abnormal MRI scans characteristic of MS but no clinical symptoms of the disease
  • Arm: People without Multiple Sclerosis or Related Disorders
    Control participants must be 7 years or older, have no known personal history of multiple sclerosis or related disorders, no other chronic disease, and can be a family member, unrelated household control, or control from the general population.

Primary Outcome Measure

Establish a prospective cohort of well-characterized MS patients and controls [ Time Frame: within 30 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of PittsburghPittsburghPennsylvania15260
Zongqi Xia, MD, PhD
412-383-5377

Find similar trials in Pittsburgh, PA

By condition
Multiple sclerosis
By specialty
NeurologyBrain disordersAutoimmune disease
By research site
University of Pittsburgh· Pittsburgh, PA

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