Early PKD Observational Cohort Study

Part of paid clinical trials in Chicago, Illinois.

Sponsor
University of Kansas Medical Center
Study ID
NCT02936791
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
4 Years - 35 Years
Healthy Volunteers
Accepted

Study Details

This observational study will collect blood and urine and clinical information from individuals with early-stages of polycystic kidney disease (PKD), their unaffected siblings and normal volunteers to create a biobank, also called a biorepository. The long-term goal is to develop new knowledge on biological markers or biomarkers that indicate changes in the disease progression. An understanding of biomarkers for early renal cyst growth will benefit PKD patients as new therapies are being developed and tested.

Key Dates

Start date
Apr 30, 2016
Status verified
Apr 2026
Primary completion
Jun 30, 2030
Completion
Jun 30, 2031

Study Design

Enrollment
250 participants (estimated)

Arms

  • Arm: Individuals diagnosed with PKD
    Individuals that have been diagnosed and meet the study's definition of early stage PKD.
  • Arm: Individuals with a family history of PKD
    Unaffected/ undiagnosed family members, preferably siblings, of participants with PKD
  • Arm: Normal individuals for the comparison
    Normal volunteers with no family history of PKD or other kidney diseases.

Primary Outcome Measure

Collect blood and urine samples from affected and unaffected cohorts for basic and translational research [ Time Frame: 10 years ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
University of ChicagoChicagoIllinois60637
Arlene Chapman, MD
[email protected]
Arlene Chapman, MD (PRINCIPAL_INVESTIGATOR)
University of Kansas Medical CenterKansas CityKansas66160
Cathy Creed, RN
[email protected]
913-588-0053
Darren P Wallace, PhD
[email protected]
913-588-3889
Children's Mercy HospitalKansas CityMissouri64108
Megan Mains, BSN
[email protected]
816-760-5918
Laurel Willig, MD, MS (PRINCIPAL_INVESTIGATOR)

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By research site
University of Chicago· Chicago, ILUniversity of Kansas Medical Center· Kansas City, KSChildren's Mercy Hospital· Kansas City, MO

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