Pancreatic Cancer Registry: For Any Person With a Personal or Family History

Conditions

• Pancreatic Cancer, ATM, BRCA, Hereditary Cancer

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Accepted

Study Details

The NFPTR was established in 1994 to find the causes of pancreatic cancer. In brief, the investigators are interested in both the genetic and non-genetic causes of pancreatic cancer. The investigators are particularly interested in finding the genes that cause pancreatic cancer to cluster in some families. Up to 10% of pancreatic cancer patients have another close relative who has also developed pancreatic cancer. This clustering of pancreatic cancers in families has yet to be explained; however, the investigators continue to identify new familial pancreatic cancer genes that explain this clustering in subsets of families. For example, in 2009 and 2012 the investigators discovered that mutations in the PALB2 and ATM genes jointly account up to 5% of the clustering of pancreatic cancer in families.

Key Dates

Start date

Jun 30, 1994

Status verified

Jul 2025

Primary completion

Jun 30, 2030

Completion

Dec 31, 2032

Study Design

Enrollment

12,000 participants (estimated)

Arms

• Arm: participants
  individuals with a personal or family history of pancreas tumors

Primary Outcome Measure

pancreatic cancer [ Time Frame: 35 years ]

Central Contacts

• Alison Klein, PhD, MHS
  410-955-3502
  [email protected]

Locations (1)

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