Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers

Part of paid clinical trials in Columbia, Missouri.

Sponsor
University of Missouri-Columbia
Study ID
NCT02838836
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Study sample collection — PROCEDURE
    Blood draws, urine and tissue asservation, and bone marrow aspiration will be done during surgery

Study Details

Patients with resectable solid primary cancers and even limited number of metastases are potentially curable. However, most patients develop recurrences despite surgery. Circulating and disseminated tumor cell (CTC/DTC) and circulating cell-free (cf) DNA isolation from the blood, urine and bone marrow will increase understanding of cancer spread and advance knowledge to develop individualized therapies.

Key Dates

Start date
Jul 1, 2016
Status verified
Apr 2026
Primary completion
Dec 1, 2027
Completion
Dec 1, 2027

Study Design

Enrollment
620 participants (estimated)

Arms

  • Arm: Study sample collection
    Blood draws, urine and tissue asservation, and bone marrow aspiration will be done during surgery

Primary Outcome Measure

CTC/DTC numbers measured in blood, urine and bone marrow samples will be correlated with patient outcome [ Time Frame: 5 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Ellis Fischel Cancer Center, University of MissouriColumbiaMissouri65212
Jussuf T Kaifi, MD, PhD
[email protected]
5738828445

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By specialty
OncologyGI oncologyLung oncologyLung disease
By research site
Ellis Fischel Cancer Center, University of Missouri· Columbia, MO

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