Study of Secukinumab Compared to Ustekinumab in Subjects With Plaque Psoriasis

Part of paid clinical trials in Anniston, Alabama.

Sponsor
Novartis Pharmaceuticals
Study ID
NCT02826603
Phase
PHASE3
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Secukinumab — DRUG
    300mg, s.c. at randomization, Weeks 1, 2 and 3 and thereafter 4-weekly till Week 48
  • Ustekinumab — DRUG
    Per approved label, 45 mg or 90 mg s.c. based on subject weight (at randomization visit) to be administered at randomization, Week 4, 16, 28 and 40. At other timepoints subjects will receive placebo injections.

Study Details

Demonstrate superiority of secukinumab over ustekinumab in treatment of moderate to severe plaque psoriasis.

Key Dates

Start date
Jun 22, 2016
Status verified
Jun 2019
Primary completion
Jul 9, 2018
Completion
Jul 9, 2018

Study Design

Enrollment
1,114 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Secukinumab
    Secukinumab
  • Active Comparator: Ustekinumab
    Ustekinumab

Primary Outcome Measure

Participants Who Achieved Psoriasis Area and Severity Index (PASI) 90 Response at Week 12 [ Time Frame: Week 12 ]

Locations (123)

FacilityCityStateZIPSite coordinators
Novartis Investigative SiteAnnistonAlabama36207-
Novartis Investigative SiteBirminghamAlabama35205-
Novartis Investigative SiteBirminghamAlabama35233-
Novartis Investigative SiteMobileAlabama36608-
Novartis Investigative SiteGlendaleArizona85308-
Novartis Investigative SitePhoenixArizona85018-
Novartis Investigative SitePhoenixArizona85032-
Novartis Investigative SiteScottsdaleArizona85259-
Novartis Investigative SiteScottsdaleArizona85260-
Novartis Investigative SiteTucsonArizona85724-
Novartis Investigative SiteFort SmithArkansas72916-
Novartis Investigative SiteHot SpringsArkansas71913-
Novartis Investigative SiteRogersArkansas72758-
Novartis Investigative SiteBakersfieldCalifornia93309-
Novartis Investigative SiteBeverly HillsCalifornia90211-
Novartis Investigative SiteCalifornia CityCalifornia93405-
Novartis Investigative SiteEncinitasCalifornia92024-
Novartis Investigative SiteFresnoCalifornia93710-
Novartis Investigative SiteFullertonCalifornia92835-
Novartis Investigative SiteIrvineCalifornia92697-
Novartis Investigative SiteLos AngelesCalifornia90033-
Novartis Investigative SiteOceansideCalifornia92056-
Novartis Investigative SiteSacramentoCalifornia95819-
Novartis Investigative SiteSan DiegoCalifornia92103-
Novartis Investigative SiteSan DiegoCalifornia92117-
Novartis Investigative SiteSan DiegoCalifornia92123-
Novartis Investigative SiteSanta MonicaCalifornia90404-
Novartis Investigative SiteSanta RosaCalifornia95405-
Novartis Investigative SiteDenverColorado80220-
Novartis Investigative SiteTrumbullConnecticut06611-
Novartis Investigative SiteAventuraFlorida33180-
Novartis Investigative SiteBoca RatonFlorida33486-
Novartis Investigative SiteCape CoralFlorida33990-
Novartis Investigative SiteCoral GablesFlorida33134-
Novartis Investigative SiteFort MyersFlorida33916-
Novartis Investigative SiteJacksonvilleFlorida32216-
Novartis Investigative SiteOrange ParkFlorida32073-
Novartis Investigative SiteSouth MiamiFlorida33143-
Novartis Investigative SiteTampaFlorida33609-
Novartis Investigative SiteTampaFlorida33624-
Novartis Investigative SiteWest Palm BeachFlorida33409-
Novartis Investigative SiteAlpharettaGeorgia30022-
Novartis Investigative SiteAtlantaGeorgia30342-
Novartis Investigative SiteMaconGeorgia31217-
Novartis Investigative SiteMariettaGeorgia30060-
Novartis Investigative SiteNewnanGeorgia30263-
Novartis Investigative SiteSkokieIllinois60077-
Novartis Investigative SiteSpringfieldIllinois62703-
Novartis Investigative SiteIndianapolisIndiana46256-
Novartis Investigative SiteNew AlbanyIndiana47150-
Novartis Investigative SiteLouisvilleKentucky40241-
Novartis Investigative SiteOwensboroKentucky42301-
Novartis Investigative SiteOwensboroKentucky42303-
Novartis Investigative SiteBaton RougeLouisiana70809-
Novartis Investigative SiteLake CharlesLouisiana70601-
Novartis Investigative SiteLake CharlesLouisiana70605-
Novartis Investigative SiteMetairieLouisiana70006-
Novartis Investigative SiteNew OrleansLouisiana70112-
Novartis Investigative SiteRockvilleMaryland20850-
Novartis Investigative SiteRockvilleMaryland20852-
Novartis Investigative SiteBeverlyMassachusetts01915-
Novartis Investigative SiteBostonMassachusetts02111-
Novartis Investigative SiteBostonMassachusetts02114-
Novartis Investigative SiteBrightonMassachusetts02135-
Novartis Investigative SiteQuincyMassachusetts02169-
Novartis Investigative SiteFridleyMinnesota55432-
Novartis Investigative SiteJacksonMississippi39216-4505-
Novartis Investigative SiteSaint JosephMissouri64506-
Novartis Investigative SiteSt LouisMissouri63104-
Novartis Investigative SiteSt LouisMissouri63117-
Novartis Investigative SiteSt LouisMissouri63141-
Novartis Investigative SiteLas VegasNevada89128-
Novartis Investigative SiteEast WindsorNew Jersey08520-
Novartis Investigative SiteVeronaNew Jersey07044-
Novartis Investigative SiteAlbuquerqueNew Mexico87106-
Novartis Investigative SiteForest HillsNew York11375-
Novartis Investigative SiteNew YorkNew York10016-
Novartis Investigative SiteNew YorkNew York10025 1737-
Novartis Investigative SiteNew YorkNew York10075-
Novartis Investigative SiteRochesterNew York14623-
Novartis Investigative SiteChapel HillNorth Carolina27516-
Novartis Investigative SiteCharlotteNorth Carolina28209-
Novartis Investigative SiteDurhamNorth Carolina27710-
Novartis Investigative SiteGreensboroNorth Carolina27401-
Novartis Investigative SiteHigh PointNorth Carolina27262-
Novartis Investigative SiteRocky MountNorth Carolina27804-
Novartis Investigative SiteWinston-SalemNorth Carolina27157-
Novartis Investigative SiteCincinnatiOhio45242-
Novartis Investigative SiteClevelandOhio44106-5028-
Novartis Investigative SiteColumbusOhio43210-
Novartis Investigative SiteDublinOhio43016-
Novartis Investigative SiteFairbornOhio45324-
Novartis Investigative SiteOklahoma CityOklahoma73103-
Novartis Investigative SiteOklahoma CityOklahoma73112-
Novartis Investigative SiteOregon CityOregon97045-
Novartis Investigative SitePortlandOregon97210-
Novartis Investigative SitePortlandOregon97223-
Novartis Investigative SiteExtonPennsylvania19341-
Novartis Investigative SiteJenkintownPennsylvania19046-
Novartis Investigative SitePittsburghPennsylvania15213-3403-
Novartis Investigative SitePlymouth MeetingPennsylvania19462-
Novartis Investigative SiteAndersonSouth Carolina29621-
Novartis Investigative SiteCharlestonSouth Carolina29407-
Novartis Investigative SiteGreerSouth Carolina29651-
Novartis Investigative SiteGoodlettsvilleTennessee37072-2301-
Novartis Investigative SiteKnoxvilleTennessee37922-
Novartis Investigative SiteMurfreesboroTennessee37130-
Novartis Investigative SiteNashvilleTennessee37203-
Novartis Investigative SiteArlingtonTexas76011-
Novartis Investigative SiteAustinTexas78705-
Novartis Investigative SiteDallasTexas75230-
Novartis Investigative SiteDallasTexas75231-
Novartis Investigative SiteHoustonTexas77056-
Novartis Investigative SitePflugervilleTexas78660-
Novartis Investigative SiteSan AntonioTexas78229-
Novartis Investigative SiteMurrayUtah84107-
Novartis Investigative SiteNorfolkVirginia23507-
Novartis Investigative SiteEverettWashington98201-
Novartis Investigative SiteSeattleWashington98101-
Novartis Investigative SiteSpokaneWashington99204-
Novartis Investigative SiteWalla WallaWashington99362-
Novartis Investigative SiteWenatcheeWashington98801-
Novartis Investigative SiteMadisonWisconsin53717-

Find similar trials in Anniston, AL

By condition
Psoriasis
By specialty
DermatologyRheumatologyAutoimmune disease
By research site
Novartis Investigative Site· Anniston, ALNovartis Investigative Site· Birmingham, ALNovartis Investigative Site· Mobile, ALNovartis Investigative Site· Glendale, AZNovartis Investigative Site· Phoenix, AZNovartis Investigative Site· Scottsdale, AZ

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