Combination of Ibrutinib and As2O3 in the Treatment of CLL
- Sponsor
- Peking University People's Hospital
- Study ID
- NCT02757040
- Phase
- PHASE3
- Status
- Unknown
Conditions
- Leukemia, Lymphocytic, Chronic, B-Cell
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 90 Years
- Healthy Volunteers
- Accepted
Interventions
- Ibrutinib combined with As2O3 — DRUGarsenic trioxide combined with ibrutinib in CLL
- ibrutinib — DRUGibrutinib
Study Details
The purpose of this study is to determine whether the combination of As2O3 and ibrutinib is synergistic in chronic lymphocytic leukemia
Key Dates
- Start date
- Dec 31, 2016
- Status verified
- Apr 2016
- Primary completion
- Dec 31, 2017
- Completion
- Dec 31, 2018
Study Design
- Enrollment
- 70 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Experimental: Ibrutinib combined with As2O3Ibrutinib combined with As2O3
- Active Comparator: IbrutinibIbrutinib only
Primary Outcome Measure
overall response rate [ Time Frame: 2 years ]
Central Contacts
- Xiao-Hui Zhang, Doctor861088324677
- Ru Feng, Doctor861085136381
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