Visceral Sensitivity in IBD (Irritable Bowel Disease) and IBS (Irritable Bowel Syndrome)

Sponsor
KU Leuven
Study ID
NCT02421705
Status
Recruiting
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Conditions

  • Crohn's Disease, Active
  • Crohn's Disease, Remission (6a: With IBS Symptoms, 6b: Without IBS Symptoms)
  • Healthy Controls
  • IBS
  • Ulcerative Colitis, Active
  • Ulcerative Colitis, Remission (3a: With IBS Symptoms, 3b: Without IBS Symptoms)

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Accepted

Interventions

  • Sample collection — OTHER
    Collection of blood, feces samples, sample of nasal mucosa and biopsies (rectum and colon descendens), questionnaires and performance of rectal sensitivity measurement (barostat), MR scan of brain and transit measurement of colon

Study Details

Aim: More insight in pathogenesis of IBS and IBD. Samples are collected in context of an European research project.

Key Dates

Start date
Feb 28, 2010
Status verified
Feb 2023
Primary completion
Jan 31, 2099
Completion
Jan 31, 2099

Study Design

Enrollment
99,999,999 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Other: Sample collection
    Collection of blood, feces samples, sample of nasal mucosa and biopsies (rectum and colon descendens), questionnaires and performance of rectal sensitivity measurement (barostat), MR scan of brain and transit measurement of colon

Primary Outcome Measure

differences in visceral sensitivity in different study groups (Visceral sensitivity will me measured by performing a rectal barostat test) [ Time Frame: at time of investigation (rectal barostat test), Day 1 ]

Central Contacts

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