Germ-Line Mutations in Blood and Saliva Samples From Patients With Cancer

Part of paid clinical trials in Los Angeles, California.

Sponsor
Jonsson Comprehensive Cancer Center
Study ID
NCT02280161
Status
Recruiting
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Conditions

  • Malignant Neoplasm

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • cytology specimen collection procedure — OTHER
    Correlative studies

Study Details

This research trial studies germ-line mutations in blood and saliva samples from patients with cancer. Studying samples of blood and saliva from patients with cancer in the laboratory may help doctors learn more about how inherited genetic mutations can affect cancer predisposition (an inherited increase in the risk of developing cancer), their impact on treatment response, and their role in cancer development.

Key Dates

Start date
Sep 16, 2014
Status verified
Nov 2025
Primary completion
Sep 16, 2026
Completion
Sep 16, 2027

Study Design

Enrollment
2,000 participants (estimated)

Arms

  • Arm: Ancillary-Correlative (germ-line mutation analysis)
    Patients undergo collection of blood and saliva samples 1-3 times at the discretion of the investigator for germ-line mutation analysis.

Primary Outcome Measure

Prevalence of germ-line variants [ Time Frame: Up to 5 years ]

Locations (1)

FacilityCityStateZIPSite coordinators
Jonsson Comprehensive Cancer CenterLos AngelesCalifornia90095
Joanne B. Weidhaas
[email protected]
310-825-9775
Joanne B. Weidhaas (PRINCIPAL_INVESTIGATOR)

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By research site
Jonsson Comprehensive Cancer Center· Los Angeles, CA

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