A Study of Ruxolitinib in Pancreatic Cancer Patients

Part of paid clinical trials in Huntsville, Alabama.

Sponsor
Incyte Corporation
Study ID
NCT02119663
Phase
PHASE3
Status
Terminated

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Ruxolitinib — DRUG
    5 mg tablets to be administered by mouth twice daily (BID)
  • Placebo — DRUG
    5 mg matching placebo tablets to be administered by mouth twice daily (BID)
  • Capecitabine — DRUG
    150 mg or 500 mg tablets to be administered by mouth twice daily (BID)

Study Details

This was to determine the efficacy, based upon overall survival, of ruxolitinib added to capecitabine for the treatment of metastatic pancreatic cancer.

Key Dates

Start date
Jun 30, 2014
Status verified
Jan 2018
Primary completion
Feb 29, 2016
Completion
Oct 31, 2016

Study Design

Enrollment
86 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Ruxolitinib plus capecitabine
  • Active Comparator: Placebo plus capecitabine

Primary Outcome Measure

Overall Survival (OS) [ Time Frame: Randomization until death due to any cause up to 6-months or to the data cutoff 11FEB2016. ]

Locations (55)

FacilityCityStateZIPSite coordinators
-HuntsvilleAlabama--
-FayettevilleArkansas--
-Beverly HillsCalifornia--
-La JollaCalifornia--
-AuroraColorado--
-DenverColorado--
-Washington D.C.District of Columbia--
-Fort MyersFlorida--
-St. PetersburgFlorida--
-AthensGeorgia--
-AtlantaGeorgia--
-MaconGeorgia--
-ThomasvilleGeorgia--
-HarveyIllinois--
-IndianapolisIndiana--
-Kansas CityKansas--
-LouisvilleKentucky--
-BaltimoreMaryland--
-BostonMassachusetts--
-Farmington HillsMichigan--
-KalamazooMichigan--
-LansingMichigan--
-MinneapolisMinnesota--
-Saint Louis ParkMinnesota--
-BolivarMissouri--
-Basking RidgeNew Jersey--
-Cherry HillNew Jersey--
-Voorhees TownshipNew Jersey--
-CommackNew York--
-Fresh MeadowsNew York--
-HarrisonNew York--
-New YorkNew York--
-RochesterNew York--
-Rockville CentreNew York--
-Sleepy HollowNew York--
-CantonOhio--
-CincinnatiOhio--
-PortlandOregon--
-AllentownPennsylvania--
-HersheyPennsylvania--
-LanghornePennsylvania--
-GreenvilleSouth Carolina--
-ChattanoogaTennessee--
-KnoxvilleTennessee--
-NashvilleTennessee--
-DallasTexas--
-Fort WorthTexas--
-LubbockTexas--
-San AntonioTexas--
-TempleTexas--
-Salt Lake CityUtah--
-Falls ChurchVirginia--
-Newport NewsVirginia--
-SeattleWashington--
-Green BayWisconsin--

Find similar trials in Huntsville, AL

By condition
Pancreatic cancer
By specialty
OncologyGI oncology

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