Study of Sonographic Efficacy of Rituximab in Rheumatoid Arthritis

Sponsor
University Hospital, Rouen
Study ID
NCT01765374
Phase
PHASE4
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • ESAOTE MyLab60 — DEVICE
    US evaluation at different time points
  • Rituximab — DRUG

Study Details

To detect by sonography relapse of disease activity prior to clinical symptoms in RA patients treated by rituximab.

Key Dates

Start date
Feb 28, 2011
Status verified
Apr 2026
Primary completion
Oct 31, 2014
Completion
Oct 31, 2014

Study Design

Enrollment
30 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: rituximab
    Only one arm; all patients are treated by rituximab (monotherapy or in combination with conventional DMARD)

Primary Outcome Measure

global score of power-doppler activity measured by ultrasonography on 12 joints [ Time Frame: at 6 months after initiation of rituximab and then every 2 month over the follow-up period (18 months) ]

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