Early Rheumatoid Arthritis Lung Disease Study

Part of paid clinical trials in Omaha, Nebraska.

Sponsor
University of Nebraska
Study ID
NCT03192267
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
19 Years - 90 Years
Healthy Volunteers
Not accepted

Study Details

Extra-articular (outside of joints) disease occurs in approximately 50% of rheumatoid arthritis (RA) patients, with the lung being a common site of involvement. The goals of this study are to investigate and characterize lung disease and its prevalence in early RA participants. This will be done through pulmonary function and high resolution chest computed tomography (CT), questionnaires, and serum studies. Another goal is to find novel biomarkers, such anti-malondialdehyde-acetaldehyde (MAA) antibodies, as predictors of lung disease in RA participants.

Key Dates

Start date
Mar 31, 2017
Status verified
Aug 2025
Primary completion
Mar 31, 2028
Completion
Mar 31, 2029

Study Design

Enrollment
100 participants (estimated)

Arms

  • Arm: No treatment
    No treatment

Primary Outcome Measure

High Resolution Computed Tomography Chest Scan Results [ Time Frame: Baseline (Visit 1 only) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Nebraska Medical CenterOmahaNebraska68198
Aimee B Schreiner, MS
[email protected]
402-559-4873
Tina A Mahajan, MD (SUB_INVESTIGATOR)
Bryant R England, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Omaha, NE

By condition
Rheumatoid arthritis
By specialty
RheumatologyAutoimmune diseaseMusculoskeletal disorders
By research site
University of Nebraska Medical Center· Omaha, NE

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