Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate But Not Responding.

Part of paid clinical trials in Anniston, Alabama.

Sponsor
AstraZeneca
Study ID
NCT01197521
Phase
PHASE3
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

The purpose of the study is to evaluate the effectiveness of two dosing regimens of fostamatinib compared to placebo, in patients with rheumatoid arthritis (RA) who are taking methotrexate but not responding. The study will last for 1 year.

Key Dates

Start date
Sep 30, 2010
Status verified
Feb 2014
Primary completion
Nov 30, 2012
Completion
Nov 30, 2012

Study Design

Enrollment
923 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Dosing Regimen A
    Oral Treatment
  • Experimental: Dosing Regimen B
    Oral Treatment
  • Placebo Comparator: Dosing Regimen C
    Oral Treatment

Primary Outcome Measure

Proportion of Patients With ACR20 at Week 24, Comparison Between Fostamatinib and Placebo. [ Time Frame: 24 weeks ]

Locations (41)

FacilityCityStateZIPSite coordinators
Research SiteAnnistonAlabama--
Research SiteHuntsvilleAlabama--
Research SiteTuscaloosaAlabama--
Research SiteTucsonArizona--
Research SiteHuntington BeachCalifornia--
Research SiteLong BeachCalifornia--
Research SiteSanta MariaCalifornia--
Research SiteSanta MonicaCalifornia--
Research SiteColorado SpringsColorado--
Research SiteBridgeportConnecticut--
Research SiteLewesDelaware--
Research SiteDaytona BeachFlorida--
Research SiteOcalaFlorida--
Research SiteAtlantaGeorgia--
Research SiteMariettaGeorgia--
Research SiteIdaho FallsIdaho--
Research SiteSpringfieldIllinois--
Research SiteWichitaKansas--
Research SiteBowling GreenKentucky--
Research SiteFlowoodMississippi--
Research SiteFlorissantMissouri--
Research SiteRichmond HeightsMissouri--
Research SiteSt LouisMissouri--
Research SiteKalispellMontana--
Research SiteAlbuquerqueNew Mexico--
Research SiteAlbanyNew York--
Research SiteBrooklynNew York--
Research SiteOleanNew York--
Research SiteAshevilleNorth Carolina--
Research SiteGreensboroNorth Carolina--
Research SitePerrysburgOhio--
Research SiteLake OswegoOregon--
Research SiteEriePennsylvania--
Research SiteWaxfordPennsylvania--
Research SiteCharlestonSouth Carolina--
Research SiteHixsonTennessee--
Research SiteMemphisTennessee--
Research SiteDallasTexas--
Research SiteHoustonTexas--
Research SiteMesquiteTexas--
Research SiteSan AntonioTexas--

Find similar trials in Anniston, AL

By condition
Rheumatoid arthritis
By specialty
RheumatologyAutoimmune diseaseMusculoskeletal disorders
By research site
Research Site· Anniston, ALResearch Site· Huntsville, ALResearch Site· Tuscaloosa, ALResearch Site· Tucson, AZResearch Site· Huntington Beach, CAResearch Site· Long Beach, CA

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