Correlation of Molecular Markers With Response to Therapy and Breast Cancer Behavior

Part of paid clinical trials in Chapel Hill, North Carolina.

Sponsor
UNC Lineberger Comprehensive Cancer Center
Study ID
NCT01000883
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • biologic sample preservation procedure — OTHER
    approximately 16-20 milligrams of tumor tissue per core will be obtained for research purposes.
  • laboratory biomarker analysis — OTHER
    Evaluation of biomarkers will occur as questions are asked in subsequent correlative studies.
  • biopsy — PROCEDURE
    cancer tissue will be taken from the primary breast cancer site as well as the metastatic tumor sites. Two tubes of whole blood will also be collected.

Study Details

RATIONALE: Studying samples of tumor tissue and blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment. PURPOSE: This research study is looking at tissue and blood samples from women with locally advanced or metastatic breast cancer

Key Dates

Start date
Dec 1, 1998
Status verified
Jun 2025
Primary completion
Nov 30, 2030
Completion
Nov 30, 2032

Study Design

Enrollment
10,000 participants (estimated)

Primary Outcome Measure

Generation of a biorepository for current and future correlative research studies [ Time Frame: Diagnosis, between treatments,7-14 days after start of treatment and at time of definitive therapy ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel HillChapel HillNorth Carolina27599-7295
Clinical Trials Office - Lineberger Comprehensive Cancer Cente
877-668-0683

Find similar trials in Chapel Hill, NC

By condition
Breast cancer
By specialty
OncologyBreast oncologyWomen's health
By research site
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill· Chapel Hill, NC

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