Abatacept Versus Adalimumab Head-to-Head

Part of paid clinical trials in Birmingham, Alabama.

Sponsor
Bristol-Myers Squibb
Study ID
NCT00929864
Phase
PHASE3
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Abatacept — DRUG
    Syringes, Subcutaneous, 125 mg/syringe for Subcutaneous, Weekly Subcutaneous injections, 24 months (729 days)
  • Adalimumab — DRUG
    Syringes, Subcutaneous, 40 mg, Biweekly Subcutaneous injections, 24 months (729 days)

Study Details

The purpose of this study is demonstrate that subcutaneous abatacept is non-inferior (no worse than) to subcutaneous adalimumab in the treatment of subjects with rheumatoid arthritis who are biologic naive

Key Dates

Start date
Oct 31, 2009
Status verified
Jan 2014
Primary completion
Oct 31, 2011
Completion
Nov 30, 2012

Study Design

Enrollment
869 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Abatacept
  • Active Comparator: Adalimumab

Primary Outcome Measure

The Proportion of Participants Meeting the American College of Rheumatology (ACR) Criteria of 20% Improvement (ACR20) After 12 Months of Treatment - Intent to Treat Population [ Time Frame: Day 1 to Day 365 ]

Locations (63)

FacilityCityStateZIPSite coordinators
Rheumatology Associates, PcBirminghamAlabama35205-
University Of Alabama At BirminghamBirminghamAlabama35294-
Clinical And Translational Research Center Of Alabama, PcTuscaloosaAlabama35406-
Sun Valley Arthritis Center, Ltd.PeoriaArizona85381-
Mercy Clinic Hot Springs CommunitiesHot SpringsArkansas71913-
Talbert Medical GroupHuntington BeachCalifornia92646-
Allergy & Rheumatology Medical Clinic, Inc.La JollaCalifornia92037-
Valerius Med Group & Res Ctr Of Greater Long Beach, Inc.Long BeachCalifornia90806-
Irene Y. TongPasadenaCalifornia91107-
San Diego Arthritis Medical ClinicSan DiegoCalifornia92108-
Drs. Goldin, Nies, Klashman & EngTorranceCalifornia90505-
Healthcare Partners Medical GroupTorranceCalifornia90503-
Inland Rheumatology & Osteoporosis Medical GroupUplandCalifornia91786-
Arthritis And Rheumatic Disease SpecialtiesAventuraFlorida33180-
University Of Florida College Of Medicine At JacksonvilleGainesvilleFlorida32610-
Center For Arthritis And Rheumatic DiseasesMiamiFlorida33173-
Arthritis Research Of Florida, Inc.Palm HarborFlorida34684-
Sarasota Arthritis Research CenterSarasotaFlorida34239-
Miami Research AssociatesSouth MiamiFlorida33143-
West Broward Rheumatology AssociatesTamaracFlorida33321-
Lovelace Scientific Resources, IncVeniceFlorida34292-
Arthritis & Rheumatology Of GeorgiaAtlantaGeorgia30342-
Laureate Clinical Research GroupAtlantaGeorgia30342-
Arthritis Center Of North GeorgiaGainesvilleGeorgia30501-
St. Luke'S Clinic - RheumatologyBoiseIdaho83702-
Coeur D'Alene Arthrit ClinCoeur d'AleneIdaho83814-
Quincy Medical GroupQuincyIllinois62301-
Rockford Orthopedic Associates, Ltd.RockfordIllinois61107-
Physicians Clinic Of IowaCedar RapidsIowa52401-
Center For Arthritis And OsteoporosisElizabethtownKentucky42701-
Bluegrass Community Research, Inc.LexingtonKentucky40504-
Klein And Associates, M.D., PaCumberlandMaryland21502-
The Center For Rheumatology And Bone ResearchWheatonMaryland20902-
Brigham And Women'S HospitalBostonMassachusetts02115-
Mansfield Health CenterMansfieldMassachusetts02048-
Associated Internal Medicine SpecialistsBattle CreekMichigan49015-
Rheumatology PcKalamazooMichigan49009-
Arthritis Associates Of MississippiJacksonMississippi39202-
Physician Groups, Lc DbaSt LouisMissouri63131-
Arthritis Center Of RenoRenoNevada89502-
Seacoast Arthritis And Osteoporosis CenterDoverNew Hampshire03820-
Nashua RheumatologyNashuaNew Hampshire03060-
Arthritis And Osteoporosis Associates Of New MexicoLas CrucesNew Mexico88011-
North Shore Lij Health SystemLake SuccessNew York11042-
Winthrop University HospitalMineolaNew York11501-
Rheumatology Associates Of Long IslandSmithtownNew York11787-
Asheville Rheumatology & Osteoporosis Research Asso P. A.AshevilleNorth Carolina28803-
Carolina Pharmaceutical ResearchStatesvilleNorth Carolina28625-
Health Research InstituteOklahoma CityOklahoma73109-
Health Research Of OklahomaOklahoma CityOklahoma73103-
Lynn Health Sciences InstituteOklahoma CityOklahoma73112-
East Penn Rheumatology Associates, P.C.BethlehemPennsylvania18015-
Altoona Center For Clinical ResearchDuncansvillePennsylvania16635-
Clinical Research Center Of Reading, LlpWyomissingPennsylvania19610-
Low Country Rheumatology, PaCharlestonSouth Carolina29406-
Columbia Arthritis Center, P.A.ColumbiaSouth Carolina29204-
Lovelace Scientific Resources, Inc.AustinTexas78758-
Arthritis Centers Of TexasDallasTexas75246-
Rheumatic Disease Clinical Research Center, LlcHoustonTexas77004-
Center For Arthritis & Rheumatic Diseases, PcChesapeakeVirginia23320-
Rockwood Research CenterSpokaneWashington99202-
Mountain State Clinical ResearchClarksburgWest Virginia26301-
Rheumatic Disease CenterGlendaleWisconsin53217-

Find similar trials in Birmingham, AL

By condition
Rheumatoid arthritis
By specialty
RheumatologyAutoimmune diseaseMusculoskeletal disorders
By research site
Rheumatology Associates, Pc· Birmingham, ALUniversity Of Alabama At Birmingham· Birmingham, ALClinical And Translational Research Center Of Alabama, Pc· Tuscaloosa, ALSun Valley Arthritis Center, Ltd.· Peoria, AZMercy Clinic Hot Springs Communities· Hot Springs, ARTalbert Medical Group· Huntington Beach, CA

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