Collection of Blood From Patients With Prostate Cancer

Conditions

• Cancer Of Prostate
• Metastatic Prostate Cancer
• Prostate
• Prostate Cancer
• Prostatic Neoplasms

Eligibility Criteria

Sex

MALE

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Study Details

Background: * It is not fully understood why prostate cancer in some men becomes androgen-independent (no longer responds to anti-androgen medication), but genetics likely plays an important role. * Genes contain the hereditary information that is passed down from parents to children. Although everyone has the same set of genes, individuals can have different forms of the same gene. * Differences in genes may explain, at least in part, why some people develop a more aggressive form of prostate cancer than others. Objectives: -To obtain blood samples from patients with prostate cancer to try to identify gene differences associated with progression to the androgen independent state. Eligibility: -All participants participating in NCI prostate cancer protocols. Design: * Participants with prostate cancer are evaluated in the NCI s Medical Oncology Clinic. * Blood samples are collected at the initial visit or at follow-up visits. * DNA (genetic material) and white blood cells are extracted from these samples to be used for genotyping and establishment of cell lines. * Gene variations are correlated with prostate cancer prognosis and prognostic indicators.

Key Dates

Start date

Feb 28, 2007

Status verified

Jan 2026

Study Design

Enrollment

1,000 participants (estimated)

Arms

• Arm: 1/Participant samples
  Blood samples from participants with diagnosed prostate cancer

Primary Outcome Measure

Acquisition and longitudinal analysis of genomic DNA, cfDNA, and cfRNA from participants with prostate cancer [ Time Frame: study duration ]

Central Contacts

• Paula A Carter, R.N.
  (240) 858-3191
  [email protected]
• William D Figg, Pharm.D.
  (240) 760-6179
  [email protected]

Locations (1)

Find similar trials in Bethesda, MD

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