Evaluation of Patients With Non-obstructive Coronary Arteries

Part of paid clinical trials in Stanford, California.

Sponsor
Stanford University
Study ID
NCT00823563
Status
Recruiting
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Conditions

  • Chest Pain
  • Ischemia

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • 30 cc blood draw — PROCEDURE
  • Intravascular ultrasound (IVUS) — PROCEDURE
  • Coronary pressure/flow wire testing — PROCEDURE
  • Coronary pressure/flow testing: Acetycholine challenge — PROCEDURE
  • Procedure: Coronary pressure/flow testing: Nitroglycerin challenge — PROCEDURE
  • Procedure: Procedure: Coronary pressure/flow testing: Adenosine challenge — PROCEDURE

Study Details

Patients with angina and non-obstructive CAD are common within clinical practice, but remain a challenge with regard to diagnosis and treatment. When these patients undergo a comprehensive evaluation at the time of invasive coronary angiography, occult coronary abnormalities are frequently found. We hope to learn the overall prevalence and presentation of these occult coronary abnormalities and its long term outcome in this patient population.

Key Dates

Start date
Jun 30, 2007
Status verified
Jun 2025
Primary completion
Jun 30, 2047
Completion
Jun 30, 2047

Study Design

Enrollment
2,000 participants (estimated)

Primary Outcome Measure

Sex Differences in Endothelial Dysfunction, Microvascular Dysfunction, and Diffuse Plaque [ Time Frame: Day of procedure (study day one) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Stanford University School of MedicineStanfordCalifornia94305
Vedant S Pargaonkar, MD (SUB_INVESTIGATOR)
Alan CY Yeung, MD (SUB_INVESTIGATOR)

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Stanford University School of Medicine· Stanford, CA

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