Vinorelbine Tartrate and Paclitaxel in Treating Older Patients With Advanced Non-Small Cell Lung Cancer

Part of paid clinical trials in Grand Island, Nebraska.

Sponsor
University of Nebraska
Study ID
NCT00602797
Phase
PHASE2
Status
Completed

Conditions

  • Recurrent Non-Small Cell Lung Carcinoma
  • Stage IV Non-Small Cell Lung Cancer

Eligibility Criteria

Sex
ALL
Age
70 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Paclitaxel — DRUG
    Given IV
  • Quality-of-Life Assessment — OTHER
    Ancillary studies
  • Questionnaire Administration — OTHER
    Ancillary studies
  • Vinorelbine Tartrate — DRUG
    Given IV

Study Details

This phase II trial studies the side effects and how well vinorelbine tartrate and paclitaxel works in treating older patients with non-small cell lung cancer that has spread to other placed in the body. Drugs used in chemotherapy, such as vinorelbine tartrate and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving combination chemotherapy may kill more tumor cells.

Key Dates

Start date
Dec 17, 2007
Status verified
Sep 2023
Primary completion
Aug 1, 2014
Completion
Aug 1, 2014

Study Design

Enrollment
20 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Treatment (vinorelbine tartrate, paclitaxel)
    Patients receive vinorelbine tartrate IV over 6-10 minutes and paclitaxel IV over 1 hour once weekly for 6 weeks.

Primary Outcome Measure

Progression-free Survival. [ Time Frame: Time from first therapy until first documentation of clinical progression, relapse or death assessed up to 5 years ]

Locations (5)

FacilityCityStateZIPSite coordinators
CHI Health Saint FrancisGrand IslandNebraska68803-
Great Plains Regional Medical CenterNorth PlatteNebraska69103-
University of Nebraska Medical CenterOmahaNebraska68198-
Veterans Administration Medical Center, OmahaOmahaNebraska68105-
Avera McKennan Hospital and University Health CenterSioux FallsSouth Dakota57105-

Find similar trials in Grand Island, NE

By research site
CHI Health Saint Francis· Grand Island, NEGreat Plains Regional Medical Center· North Platte, NEUniversity of Nebraska Medical Center· Omaha, NEVeterans Administration Medical Center, Omaha· Omaha, NEAvera McKennan Hospital and University Health Center· Sioux Falls, SD

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