The DISTAL-2 Study: Docetaxel Alone or in Combination in Second-line Treatment of Advanced Non Small-Cell Lung Cancer
- Sponsor
- National Cancer Institute, Naples
- Study ID
- NCT00345059
- Phase
- PHASE3
- Status
- Terminated
Conditions
- Advanced Non-Small Cell Lung Cancer
Eligibility Criteria
- Sex
- ALL
- Age
- N/A - 75 Years
- Healthy Volunteers
- Not accepted
Interventions
- docetaxel — DRUG
- vinorelbine — DRUG
- gemcitabine — DRUG
- capecitabine — DRUG
Study Details
The purpose of this study is to compare the overall survival of patients with advanced non small cell lung cancer treated with docetaxel as single therapy versus docetaxel in combination with either gemcitabine or vinorelbine or in combination with capecitabine.
Key Dates
- Start date
- May 31, 2005
- Status verified
- Jan 2016
- Primary completion
- May 31, 2008
- Completion
- May 31, 2008
Study Design
- Enrollment
- 84 participants (actual)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Active Comparator: docetaxelsingle agent docetaxel
- Experimental: docetaxel + vinorelbine OR gemcitabinedocetaxel in combination with either vinorelbine or with gemcitabine
- Experimental: docetaxel + capecitabinedocetaxel in combination with capecitabine
Primary Outcome Measure
overall survival [ Time Frame: one year ]
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