Magnetic Resonance Spectroscopy Studies of Cardiac Muscle Metabolism

Part of paid clinical trials in Baltimore, Maryland.

Sponsor
Johns Hopkins University
Study ID
NCT00181259
Status
Recruiting
Apply to this trial

Conditions

  • Heart Failure, Congestive

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Study Details

The metabolism of the heart provides the chemical energy needed to fuel ongoing normal heart contraction. Magnetic resonance spectroscopy is a technique used in a MRI scanner that can be used to measure and study heart metabolism directly but without blood sampling or obtaining tissue biopsies. One of the hypotheses this study aims to investigate is whether energy metabolism is reduced in heart failure and whether that contributes to the poor heart function.

Key Dates

Start date
Jan 31, 1988
Status verified
Mar 2026
Primary completion
Aug 31, 2027
Completion
Aug 31, 2028

Study Design

Enrollment
500 participants (estimated)

Primary Outcome Measure

Phosphocreatine/adenosine triphosphate (PCr/ATP) and creatine kinase (CK) flux [ Time Frame: At time of magnetic resonance spectroscopy (MRS) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Johns Hopkins Medical InstitutionsBaltimoreMaryland21205
Tricia Steinberg, RN, MSN
[email protected]
443-287-3469

Find similar trials in Baltimore, MD

By research site
Johns Hopkins Medical Institutions· Baltimore, MD

Related Studies