Study of the Human Anti-TNF Monoclonal Antibody Adalimumab for the Induction of Clinical Remission in Subjects With Crohn's Disease

Part of paid clinical trials in Huntsville, Alabama.

Sponsor
Abbott
Study ID
NCT00105300
Phase
PHASE3
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

Study Details

The goal of this study is to test whether adalimumab can induce clinical remission in subjects with active Crohn's disease who have been initially treated with infliximab and either lost response or discontinued its use as a result of intolerance to the drug.

Key Dates

Start date
Oct 31, 2004
Status verified
Aug 2006

Study Design

Enrollment
300 participants
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Primary Outcome Measure

Induction of clinical remission (CDAI score < 150 at Week 4)

Locations (46)

FacilityCityStateZIPSite coordinators
Clinical Research AssociatesHuntsvilleAlabama35801-
Capitol Gastroenterology Consultants Medical Group, Inc.RosevilleCalifornia95661-
Medical Associates Research GroupSan DiegoCalifornia92123-
Sharp Rees-Stealy Medical GroupSan DiegoCalifornia92123-
SMC-Trauma ResearchEnglewoodColorado80113-
Clinical Research of West Florida, IncClearwaterFlorida33765-
V.A. Medical CenterGainesvilleFlorida32608-
Borland-Groover ClinicJacksonvilleFlorida32256-
Shafran Gastroenterology CenterWinter ParkFlorida32789-
Atlanta Gastroenterology Assoc.AtlantaGeorgia30342-
Pinnacle Trials, Inc.AtlantaGeorgia30329-
The University of ChicagoChicagoIllinois60673-
Ntouch ResearchPeoriaIllinois60602-
Outpatient Clinical Research Facility University of IndianapolisIndianapolisIndiana462025250-
University of Kentucky Medical Center Division of Digestive DiseasesLexingtonKentucky40536-
Drug Research Services, Inc.MetairieLouisiana70001-
Chevy Chase Clinical ResearchChevy ChaseMaryland20815-
Charm City ResearchTowsonMaryland21204-
Minnesota Gastroenterology P.A.PlymouthMinnesota55446-
Mayo Clinic ResearchRochesterMinnesota559050002-
Gastrointestinal Associated, P.A.JacksonMississippi39202-
Glen Gordon, MDMexicoMissouri65265-
St. Louis Center for Clinical ResearchSt LouisMissouri63128-
Atlantic Gastroenterology Associates, LLCEgg HarborNew Jersey08234-
Long Island Clinical Research Assoc. LLPGreat NeckNew York11021-
NY Center for Clinical ResearchLake SuccessNew York11042-
Mount Sinai School of Medicine IBD Research CenterNew YorkNew York10029-
Asheville Gastroenterology AssociatesAshvilleNorth Carolina28801-
Wake Research AssociatesRaleighNorth Carolina27612-
Consultants for Clinical ResearchCincinnatiOhio45219-
Cleveland Clinic FoundationClevelandOhio44195-
Gastrointestinal and Liver Disease ConsultantsDaytonOhio45440-
Gastroenterology Associates of ClevelandMayfield HeightsOhio44124-
The Oregon Clinic, PC Gastroenterology DivisionPortlandOregon97220-
Regional Gastroenterologist Associates of LancasterLancasterPennsylvania17604-
University of Pittsburgh Medical CenterPittsburghPennsylvania15261-
Columbia Gastro AssociatesColumbiaSouth Carolina29204-
Gastrointestinal AssociatesKnoxvilleTennessee37909-
Gastroenterology Center of the Mid SouthMemphisTennessee38120-
Vanderbilt University Medical CenterNashvilleTennessee37232-
Austin GastroenterologyAustinTexas78745-
Wasatch Clinical ResearchSalt Lake CityUtah84107-
Internal Medicine AssociatesDanvilleVirginia25451-
Digestive and Liver DiseaseNorfolkVirginia23205-
Spokane Digestive Disease CenterSpokaneWashington99204-
Discovery Research International, LLCMilwaukeeWisconsin53207-

Find similar trials in Huntsville, AL

By condition
Crohn's disease
By specialty
GastroenterologyInflammatory bowel diseaseAutoimmune disease
By research site
Clinical Research Associates· Huntsville, ALCapitol Gastroenterology Consultants Medical Group, Inc.· Roseville, CAMedical Associates Research Group· San Diego, CASharp Rees-Stealy Medical Group· San Diego, CASMC-Trauma Research· Englewood, COClinical Research of West Florida, Inc· Clearwater, FL

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