Irinotecan in Treating Aging Patients With Solid Tumors

Part of paid clinical trials in La Jolla, California.

Sponsor
Alliance for Clinical Trials in Oncology
Study ID
NCT00026195
Phase
PHASE1
Status
Completed

Conditions

  • Unspecified Adult Solid Tumor, Protocol Specific

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Aging may affect the way these drugs work. PURPOSE: Phase I trial to determine the relationship between aging and the effectiveness of irinotecan in treating patients who have solid tumors.

Key Dates

Start date
Sep 30, 2001
Status verified
Jul 2016
Primary completion
Jun 30, 2006
Completion
Jun 30, 2006

Study Design

Enrollment
140 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: irinotecan
    Patients receive irinotecan IV over 90 minutes once weekly for 4 weeks. Treatment continues in the absence of disease progression or unacceptable toxicity. Patients are followed for survival.

Primary Outcome Measure

overall survival [ Time Frame: Up to 10 years ]

Locations (47)

FacilityCityStateZIPSite coordinators
Rebecca and John Moores UCSD Cancer CenterLa JollaCalifornia92093-0658-
Cedars-Sinai Medical CenterLos AngelesCalifornia90048-
UCSF Comprehensive Cancer CenterSan FranciscoCalifornia94143-0128-
Veterans Affairs Medical Center - San FranciscoSan FranciscoCalifornia94121-
CCOP - Christiana Care Health ServicesWilmingtonDelaware19899-
Lombardi Cancer CenterWashington D.C.District of Columbia20007-
Walter Reed Army Medical CenterWashington D.C.District of Columbia20307-5000-
CCOP - Mount Sinai Medical CenterMiami BeachFlorida33140-
MBCCOP - University of Illinois at ChicagoChicagoIllinois60612-7323-
University of Chicago Cancer Research CenterChicagoIllinois60637-1470-
Veterans Affairs Medical Center - Chicago (Westside Hospital)ChicagoIllinois60612-
CCOP - Northern Indiana CR ConsortiumSouth BendIndiana46601-
Holden Comprehensive Cancer CenterIowa CityIowa52242-1009-
Marlene and Stewart Greenebaum Cancer Center, University of MarylandBaltimoreMaryland21201-
Dana-Farber Cancer InstituteBostonMassachusetts02115-
University of Massachusetts Memorial Medical Center - University CampusWorcesterMassachusetts01655-
University of Minnesota Cancer CenterMinneapolisMinnesota55455-
Veterans Affairs Medical Center - MinneapolisMinneapolisMinnesota55417-
Ellis Fischel Cancer Center - ColumbiaColumbiaMissouri65203-
Veterans Affairs Medical Center - Columbia (Truman Memorial)ColumbiaMissouri65201-
Barnes-Jewish HospitalSt LouisMissouri63110-
Missouri Baptist Cancer CenterSt LouisMissouri63131-
University of Nebraska Medical CenterOmahaNebraska68198-7680-
CCOP - Southern Nevada Cancer Research FoundationLas VegasNevada89106-
Norris Cotton Cancer CenterLebanonNew Hampshire03756-0002-
Roswell Park Cancer InstituteBuffaloNew York14263-0001-
Veterans Affairs Medical Center - BuffaloBuffaloNew York14215-
CCOP - North Shore University HospitalManhassetNew York11030-
North Shore University HospitalManhassetNew York11030-
Memorial Sloan-Kettering Cancer CenterNew YorkNew York10021-
Mount Sinai Medical Center, NYNew YorkNew York10029-
Weill Medical College of Cornell UniversityNew YorkNew York10021-
CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C.SyracuseNew York13217-
State University of New York - Upstate Medical UniversitySyracuseNew York13210-
Veterans Affairs Medical Center - SyracuseSyracuseNew York13210-
Lineberger Comprehensive Cancer Center, UNCChapel HillNorth Carolina27599-7295-
Duke Comprehensive Cancer CenterDurhamNorth Carolina27710-
Veterans Affairs Medical Center - DurhamDurhamNorth Carolina27705-
CCOP - Southeast Cancer Control ConsortiumWinston-SalemNorth Carolina27104-4241-
Comprehensive Cancer Center at Wake Forest UniversityWinston-SalemNorth Carolina27157-1082-
Arthur G. James Cancer Hospital - Ohio State UniversityColumbusOhio43210-1240-
Western Pennsylvania HospitalPittsburghPennsylvania15224-
Lifespan: The Miriam HospitalProvidenceRhode Island02906-
Green Mountain Oncology GroupBenningtonVermont05201-
Vermont Cancer CenterBurlingtonVermont05401-3498-
Veterans Affairs Medical Center - White River JunctionWhite River JunctionVermont05009-
MBCCOP - Massey Cancer CenterRichmondVirginia23298-0037-

Find similar trials in La Jolla, CA

By research site
Rebecca and John Moores UCSD Cancer Center· La Jolla, CACedars-Sinai Medical Center· Los Angeles, CAUCSF Comprehensive Cancer Center· San Francisco, CAVeterans Affairs Medical Center - San Francisco· San Francisco, CACCOP - Christiana Care Health Services· Wilmington, DELombardi Cancer Center· Washington D.C., DC

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