Genomic Profiling in Recommending Treatment for Patients With Metastatic Solid Tumors

Part of paid clinical trials in Palo Alto, California.

Sponsor
Stanford University
Study ID
NCT02215928
Status
Recruiting
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Conditions

  • Unspecified Adult Solid Tumor, Protocol Specific

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • mutation analysis — GENETIC
    Correlative studies
  • cytology specimen collection procedure — OTHER
    Correlative studies
  • laboratory biomarker analysis — OTHER
    Correlative studies

Study Details

This research trial studies using genomic profiling to recommend anticancer treatment to patients with cancer that has spread beyond the original site of the tumor (metastatic cancer). Genomic profiling studies the deoxyribonucleic acid (DNA) of a tumor to detect genetic changes or abnormalities. This information can then be used to recommend treatments that may be more likely to result in a beneficial response. It is not yet known whether genomic profiling will detect abnormalities that can be used to make treatment recommendations and whether treatment based on genomic profiling is more effective than standard treatment.

Key Dates

Start date
Jul 28, 2014
Status verified
Dec 2025
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
100 participants (estimated)

Arms

  • Arm: Ancillary-correlative (tumor genomic profiling)
    Tissue samples are collected at baseline and blood for liquid biopsy is collected at baseline and every 6-8 weeks during active treatment. Tissue samples are analyzed via sequencing for tumor genomic profiling.

Primary Outcome Measure

Feasibility, measured as the proportion of patients with at least one actionable alteration [ Time Frame: Baseline ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Stanford UniversityPalo AltoCalifornia94305
Rozelle Laquindanum
[email protected]
650-724-9948
James M Ford, MD (PRINCIPAL_INVESTIGATOR)

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