Natural History of Stroke: Cause and Development

Part of paid clinical trials in Washington D.C., District of Columbia.

Sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
Study ID
NCT00009243
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 120 Years
Healthy Volunteers
Not accepted

Study Details

The purpose of this study is to learn more about stroke and obtain information that may serve as the basis for future investigations. It will 1) establish a registry of patients with cerebrovascular disease (stroke); 2) characterize the natural history of acute stroke and transient ischemic attacks (TIA)-an interruption of blood flow to the brain that causes stroke symptoms for a short period of time); and 3) evaluate the data to generate ideas for future studies. Patients 18 years of age or older with suspected acute stroke or TIA may be eligible for this study. Subjects will be recruited from patients who present with stroke at the emergency department of Suburban Hospital in Bethesda, Maryland. The study will gather data collected from diagnostic and laboratory tests the patient undergoes as part of standard medical care, including findings of medical and neurological examinations and other tests. In addition, studies will be done for research purposes only to gather data about stroke and TIA. These may include the following: * Blood and urine tests not more than 2 tablespoons of blood will be drawn for various tests. * Electrocardiogram (EKG) (heart tracing)-electrodes placed on the chest wall detect the heartbeat and heart rhythm. * Computed tomography (CT) scan of the head-specialized X-rays are used to obtain images of the brain. * Magnetic resonance imaging (MRI) of the brain-a strong magnetic field and radio waves are used to produce images that provide information about the brain tissue and blood vessels. * Transcranial Doppler (TCD)-sound waves are used to image the arteries of the brain and neck. * Echocardiogram-sound waves are used to image the heart and evaluate heart function. Patients may be asked to return to Suburban Hospital for follow-up testing in 1, 3, and/or 12 months, when some of these tests may be repeated to assess changes over time ...

Key Dates

Start date
Jan 26, 2001
Status verified
Apr 2026

Study Design

Enrollment
4,000 participants (estimated)

Arms

  • Arm: Patients
    Patients with acute stroke symptoms

Primary Outcome Measure

Prevalence and type of abnormalities seen on neuroimaging as a function of time from acute insult [ Time Frame: Post-acute, 24 hours, 5 days/discharge, 30 days ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
Medstar Washington Hospital CenterWashington D.C.District of Columbia20010
Lawrence Latour, Ph.D.
[email protected]
301-435-2395
National Institutes of Health Clinical CenterBethesdaMaryland20892
For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)
[email protected]
800-411-1222
Suburban Hospital - Johns Hopkins MedicineBethesdaMaryland20814
Lawrence Latour, Ph.D.
[email protected]
301-435-2395

Find similar trials in Washington D.C., DC

By condition
Stroke
By specialty
NeurologyBrain disorders
By research site
Medstar Washington Hospital Center· Washington D.C., DCNational Institutes of Health Clinical Center· Bethesda, MDSuburban Hospital - Johns Hopkins Medicine· Bethesda, MD

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