Olimersen and Irinotecan in Treating Patients With Metastatic or Recurrent Colorectal Cancer
Part of paid clinical trials in Cleveland, Ohio.
- Sponsor
- The University of Texas Health Science Center at San Antonio
- Study ID
- NCT00004870
- Phase
- PHASE1/PHASE2
- Status
- Completed
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- oblimersen sodium — BIOLOGICAL
- irinotecan hydrochloride — DRUG
Study Details
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Gene therapy such as oblimersen may make tumor cells more sensitive to chemotherapy drugs. Combining irinotecan and oblimersen may kill more tumor cells. PURPOSE: Phase I/II trial to study the effectiveness of combining oblimersen and irinotecan in treating patients who have metastatic or recurrent colorectal cancer.
Key Dates
- Start date
- Jun 30, 2000
- Status verified
- Feb 2013
- Primary completion
- Sep 30, 2002
- Completion
- Sep 30, 2002
Study Design
- Primary purpose
- TREATMENT
Locations (3)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Ireland Cancer Center | Cleveland | Ohio | 44106-5065 | - |
| Brooke Army Medical Center | Fort Sam Houston | Texas | 78234 | - |
| San Antonio Cancer Institute | San Antonio | Texas | 78229 | - |
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