Irinotecan in Treating Patients With Metastatic or Recurrent Colorectal Cancer

Part of paid clinical trials in Cleveland, Ohio.

Sponsor
Case Comprehensive Cancer Center
Study ID
NCT00002933
Phase
PHASE2
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 120 Years
Healthy Volunteers
Not accepted

Interventions

  • irinotecan hydrochloride — DRUG
    Irinotecan IV at a starting dose weekly for 4 weeks followed by 2 weeks of rest. Treatment continues in the absence of disease progression or unacceptable toxicity. Tumor status is reassessed every 12 weeks during study. Patients attaining a complete response may receive additional courses of treatment. Patients are followed until death.

Study Details

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of irinotecan in treating patients who have metastatic or recurrent colorectal cancer.

Key Dates

Start date
Sep 30, 1996
Status verified
Jul 2020
Primary completion
Jul 31, 2000
Completion
Jan 31, 2001

Study Design

Enrollment
21 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Primary Outcome Measure

Effectiveness of irinotecan in treating patients who have metastatic or recurrent colorectal cancer. [ Time Frame: Starting dose weekly for 4 weeks followed by 2 weeks of rest. Treatment continues in the absence of disease progression or unacceptable toxicity. Tumor status is reassessed every 12 weeks during study. ]

Locations (2)

FacilityCityStateZIPSite coordinators
Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer CenterClevelandOhio44106-5065-
Veterans Affairs Medical Center - ClevelandClevelandOhio44106-

Find similar trials in Cleveland, OH

By condition
Colorectal cancer
By specialty
OncologyGI oncology
By research site
Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center· Cleveland, OHVeterans Affairs Medical Center - Cleveland· Cleveland, OH

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