New Haven, CT Clinical Trials Report — April 2026

For New Haven residents considering clinical trial participation, April 2026 presents a critical window to join studies before enrollment concludes. A total of 49 clinical trials are slated to close within the next 90 days, with 8 of these still actively seeking healthy volunteers. This urgency means now is an opportune time to explore these options and contribute to medical advancements.

Trials Nearing Conclusion

Patients managing specific health conditions also face impending deadlines to join research. Trials focused on various cancers, metabolic disorders, and cardiovascular health are among those with limited time remaining for enrollment. Conditions with trials closing soon include:

• Advanced solid tumor (2 trials)
• Deep venous thrombosis (2 trials)
• Stage IV lung cancer AJCC V8 (2 trials)
• Type 2 diabetes (2 trials)
• Healthy volunteer (2 trials)
• Aerobic capacity (1 trial)
• Advanced solid tumors (1 trial)
• Advanced breast cancer (1 trial)
• All, adult (1 trial)
• Alcohol withdrawal (1 trial)

If you or someone you know has one of these conditions, acting quickly could provide an opportunity to access cutting-edge research before these studies close to new participants.

New Research Opportunities This Month

New Haven continues to be a vibrant center for medical research, with 11 new trials opening this month, an increase from the 7 new trials that launched in March 2026. This brings the total number of recruiting trials in New Haven to 829 across 274 research facilities.

Several notable new trials have begun recruiting, offering unique opportunities for participation:

• Yale University is sponsoring NCT07519733, "Preoperative Exercise Testing and Perioperative Outcomes." This observational study aims to understand if results from a brief exercise test performed before surgery can help identify adults, specifically those older than 45 years, who might be more likely to experience problems after moderate- to high-risk noncardiac surgery. The study plans to enroll 992 participants.
• Also from Yale University, NCT07515846, "Breast Cancer Screening Decision Aid," is a randomized survey study comparing two decision aids for breast cancer screening—a video-based tool versus a written one. This study seeks 300 participants to assess the impact of these different formats on patient understanding and decision-making.
• Another significant trial from Yale University is NCT07549126, "Adaptive Decision Support for Addiction Treatment (ADAPT) Serial Randomized Testing for Usability, Round 1." This study, aiming for 300 participants, is part of a larger effort to refine and optimize a clinical decision support system (EMBED) to improve care for patients with opioid use disorder in emergency departments.

New trials this month are exploring a diverse range of conditions, including alcohol use disorder (2 trials), chronic kidney disease (1 trial), obesity (1 trial), and Netherton syndrome (1 trial). The majority of these new studies are behavioral (4 trials) or drug-related (4 trials), with single device, diagnostic test, and other types of trials also opening.

Beyond Yale University, other sponsors contributing to New Haven's research landscape this month include industry leaders like Pfizer, Arsenal Medical, Inc., Newleos Therapeutics, Inc., and Quoin Pharmaceuticals, indicating a mix of academic and industry-driven innovation.

Opportunities for Healthy Volunteers

For individuals without a specific medical condition, there are significant opportunities to contribute to medical science. Of the 11 new trials launched this month, 5 are actively seeking healthy volunteers. Overall, New Haven currently has 95 clinical trials recruiting healthy participants, providing numerous avenues for those interested in supporting research without a specific diagnosis.

A Hub of Innovation: New Haven's Leading Research Facilities

New Haven is home to some of the nation's leading research institutions, which consistently run a high volume of clinical trials. These facilities are key destinations for individuals seeking to participate in medical research:

• Yale University (251 trials)
• Yale Cancer Center (72 trials)
• Yale New Haven Hospital (58 trials)
• Yale University School of Medicine (48 trials)
• Yale School of Medicine (36 trials)
• Smilow Cancer Center/Yale-New Haven Hospital (22 trials)
• Connecticut Mental Health Center (10 trials)

These institutions, particularly those affiliated with Yale, offer a broad spectrum of research, from oncology at Yale Cancer Center and Smilow Cancer Center to diverse medical fields across Yale University and Yale New Haven Hospital. The Connecticut Mental Health Center also plays a vital role in mental health research within the city.

Expanding Your Search: Nearby Connecticut Options

While New Haven offers a vast array of clinical trial opportunities, individuals may also find options in nearby communities within Connecticut. Cities with active trials include Fairfield (1 trial), Guilford (1 trial), Hartford (1 trial), Stamford (1 trial), Waterbury (1 trial), and West Haven (1 trial). Exploring these neighboring areas could broaden the scope of available studies.

Who Can Participate?

Participation in clinical trials is open to a diverse range of individuals. Of the 11 new trials launched this month, 10 include older adults, ensuring that senior populations have ample opportunity to contribute to medical science. Additionally, 1 new trial is specifically designed for female participants, and 1 trial includes children. Academic institutions, particularly Yale University, continue to drive the majority of research in New Haven, sponsoring 7 of the new trials this month, while industry sponsors contribute the remaining 4, highlighting a collaborative research environment.

As we look ahead, New Haven's robust research community will continue to explore new therapeutic strategies and advance medical understanding, offering ongoing opportunities for those wishing to contribute to health innovation.