As of June 2026, 15 paid clinical trials are recruiting for Non-small cell lung cancer (NSCLC) in Tyler, Texas. Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Tyler has approximately 166 recruiting research studies across a wide range of therapeutic areas. Texas hosts major cancer and cardiovascular research centers including MD Anderson Cancer Center, Baylor College of Medicine, UT Southwestern Medical Center, and the Texas Medical Center — the largest medical complex in the world.
Researchers run research studies in Tyler, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Texas Oncology - Northeast Texas | Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC) | 21 |
| Tyler Research Institute, LLC | Crohn's Disease, Ulcerative Colitis, Colitis, Ulcerative | 14 |
| CHRISTUS Trinity Mother Frances Health System | Atrial Fibrillation, Beta-blocker Therapy, Cardiomyopathy | 8 |
| Texas Oncology | Advanced/Metastatic Solid Tumors, Colorectal Cancer, Esophageal Cancer | 5 |
| Texas Oncology - Tyler | Breast Cancer, Bone Metastases From Solid Tumors, Cancer | 5 |
| Tyler Research Institute | Ulcerative Colitis, Obesity or Overweight, Crohn's Disease | 5 |
| The University of Texas Health Science Center at Tyler dba UT Health East Texas HOPE Cancer Center | Non-small Cell Lung Cancer, Triple-Negative Breast Cancer, Breast Neoplasms | 5 |
| Precision Spine Care | Degenerative Disc Disease, Degenerative Disc Disease (DDD), Disc Degeneration | 4 |
| Texas Oncology - Northeast | Advanced Lung Cancer, Carcinoma, Non-Small-Cell Lung, Leukemia, Myeloid, Acute | 4 |
| HOPE Cancer Center of East Texas | Follicular Lymphoma (FL), Pancreatic Cancer Metastatic, Pancreatic Cancer Stage IV | 3 |
| Texas Oncology, P.A. - Tyler | Gastric Cancer, Gastroesophageal Junction Cancer, Metastatic Castration-resistant Prostate Cancer | 3 |
| Texas Oncology-Northeast Texas | Breast Cancer, Breast Neoplasms, Non-Small Cell Lung Cancer Metastatic | 3 |
| Tyler Retina Consultants | DME, Diabetic Macular Edema, Diabetic Macular Edema (DME) | 3 |
| University of Texas Health Center at Tyler | KRAS G12C Lung Cancer, Moderately to Severely Active Crohns Disease, Moderately to Severely Active Ulcerative Colitis | 3 |
| GSK Investigational Site | Multiple Myeloma, Neoplasms, Newly Diagnosed Multiple Myeloma | 2 |
| Texas Oncology Northeast Texas | Extensive Stage Small-cell Lung Cancer, Metastatic Castration-resistant Prostate Cancer, Small-cell Lung Cancer | 2 |
| Texas Oncology Tyler | Chronic Lymphocytic Leukemia, CLL, Small Lymphocytic Lymphoma | 2 |
| Texas Oncology, P.A. - Oncology | Advanced Solid Tumor, Limited-stage Small Cell Lung Cancer (LS-SCLC), Malignant Peripheral Nerve Sheath Tumors | 2 |
| Texas Oncology- Northeast Texas | B-Cell Non-Hodgkins Lymphoma, Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC) | 2 |
| Texas Oncology-Tyler | Non-Small Cell Lung Cancer, Ovarian Cancer | 2 |
| The University of Texas Health Science Center at Tyler | Carcinoma, Non-Small-Cell Lung, Extensive Stage Small Cell Lung Cancer (ES-SCLC) | 2 |
| Tyler Cardiovascular Consultants | Atrial Fibrillation (AF), Cardiovascular Disease | 2 |
| UT Health East Texas HOPE Cancer Center | Carcinoma, Non-Small Cell Lung, Colorectal Neoplasms, Cutaneous Squamous Cell Cancer | 2 |
| University of Texas Health Science Center at Tyler | Bronchiectasis, Extensive Stage Small-cell Lung Cancer, Small-cell Lung Cancer | 2 |
| University of Texas at Tyler | Metastatic Solid Tumors, Non-Small Cell Lung Cancer | 2 |
Recruiting trials in Tyler grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Clinical trials in Texas are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Trials run in Texas must also comply with the Texas Medical Privacy Act (TMPA), which extends federal HIPAA protections to a broader range of entities handling participant data.
Hipa.ai aggregates every recruiting study in Tyler from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
There are approximately 166 recruiting clinical trials in Tyler, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Tyler compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Tyler include Crohn's Disease (11), Ulcerative Colitis (8), Multiple Myeloma (6), Endometrial Cancer (5), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Tyler on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Tyler include Texas Oncology - Northeast Texas, Tyler Research Institute, LLC, CHRISTUS Trinity Mother Frances Health System, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Tyler are Cancer & tumors (83), Cardiovascular (16), Eye & vision (7). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.