Paid Clinical Trials in Tupelo, MS
As of June 2026, 35 paid clinical trials are recruiting in Tupelo, Mississippi. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Tupelo offers studies at sites including North Mississippi Medical Center for conditions such as Cardiovascular Diseases, Heart Failure, Atrial Fibrillation, Chronic Kidney Diseases. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Tupelo
Trials by drug in Tupelo
Filter results
35 clinical trials
↓ Download CSVA Study of DII235 in Adults With Elevated Lipoprotein(a)
A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer
A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China
MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels
SPYRAL GEMINI Pilot Study
Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease
A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease
A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)
ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB
The CONFORM Pivotal Trial
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
Assessment of CCM in HF With Higher Ejection Fraction
Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
Selatogrel Outcome Study in Suspected Acute Myocardial Infarction
Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
About research studies in Tupelo
Tupelo has approximately 35 recruiting research studies across a wide range of therapeutic areas. Mississippi hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in Tupelo
Researchers run research studies in Tupelo, MS at 19 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| North Mississippi Medical Center | Cardiovascular Diseases, Acute Myocardial Infarction (AMI), Atrial Fibrillation | 6 |
| Cardiology Associates of North Mississippi | Atherosclerotic Cardiovascular Disease, Obesity, Overweight | 3 |
| North Mississippi Hematology and Oncology Associates | Neoplasm Metastasis, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung | 3 |
| Cardiology Associates Research, LLC | Cardiovascular Diseases, Coronary Artery Disease, In-Stent Restenosis | 3 |
| Cardiolg Assoc Rsch LLC_Tupelo | Acute Myocardial Infarction (AMI), Cardiovascular Risk, Heart Failure | 2 |
| Cardiology Associates of North MS | Atrial Fibrillation, Lipoprotein Disorder | 2 |
| - Nephrology and Hypertension Associates Ltd | Atherosclerotic Cardiovascular Disease in Patients With ESKD | 1 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis | 1 |
| Anthos Investigative | Atrial Fibrillation (AF) | 1 |
| CARE Institute - Nephrology & Hypertension Associates | FSGS | 1 |
| Cardiology Associates Research | Acute Myocardial Infarction | 1 |
| Cardiology Associates Research LLC | Cardiovascular Disease | 1 |
| Clinical Trial Site | High Cardiovascular Risk, High Risk Cardiovascular Disease, Hypertension | 1 |
| Digestive Health Specialists | Ulcerative Colitis | 1 |
| Nephrology & Hypertension Associates Ltd - Tupelo | Chronic Kidney Disease, Receiving Dialysis, Dialysis, ESRD (End-Stage Renal Disease) | 1 |
| Nephrology and Hypertension Associates | Chronic Kidney Diseases, Type 2 Diabetes Mellitus | 1 |
| Nephrology and Hypertension Associates - Tupelo | Proteinuric Kidney Disease | 1 |
| SOG Surgery Center | Lumbar Spinal Stenosis | 1 |
| Tupelo, MS Investigative | Acute Heart Failure, Heart Failure | 1 |
Active & Upcoming Studies in Tupelo (2026)
Recruiting trials in Tupelo grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cardiovascular (12 active studies)
- A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation · Phase 2 · Novartis Pharmaceuticals
- Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease · Phase 3 · Alnylam Pharmaceuticals
Diabetes & metabolic (4 active studies)
Cancer & tumors (1 active study)
Neurology & pain (1 active study)
- The CONFORM Pivotal Trial · Conformal Medical, Inc
Common conditions studied in Tupelo
- Cardiovascular Diseases (3 active studies). Recruiting Cardiovascular Diseases studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Heart Failure (3 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Atrial Fibrillation (2 active studies). Atrial fibrillation studies investigate next-generation anticoagulants, ablation technologies, and left atrial appendage closure devices.
- Chronic Kidney Diseases (2 active studies). Kidney disease trials investigate SGLT-2 inhibitors, mineralocorticoid receptor antagonists, and novel antifibrotic therapies to slow progression.
- Coronary Artery Disease (2 active studies). Coronary artery disease research evaluates lipid-lowering therapies, anti-inflammatory agents, and new revascularization devices.
- Hypertension (2 active studies). Hypertension research tests new antihypertensive drug classes, renal denervation devices, and fixed-dose combinations for resistant disease.
Leading research sponsors in Tupelo
- Eli Lilly and Company
- Novo Nordisk A/S
- Amgen
- AstraZeneca
- Concept Medical Inc.
Local regulations and guidelines
Clinical trials in Mississippi are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Mississippi research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Tupelo. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Tupelo
Hipa.ai aggregates every recruiting study in Tupelo from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Tupelo?
There are approximately 35 recruiting clinical trials in Tupelo, Mississippi listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Tupelo pay participants?
Most recruiting trials in Tupelo compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Tupelo?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Tupelo?
The most common conditions under active study in Tupelo include Cardiovascular Diseases (3), Heart Failure (3), Atrial Fibrillation (2), Chronic Kidney Diseases (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Tupelo?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Tupelo on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Tupelo?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Tupelo?
Recruiting research sites in Tupelo include North Mississippi Medical Center, Cardiology Associates of North Mississippi, North Mississippi Hematology and Oncology Associates, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Tupelo right now?
The largest active categories in Tupelo are Cardiovascular (12), Diabetes & metabolic (4), Cancer & tumors (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.