Paid Clinical Trials in Tennessee

Tennessee has 2,155 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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2,155 clinical trials

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The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study

for Metastatic Breast Cancer

73 locations incl. Chandler

Sponsor: American Society of Clinical Oncology

Sex: All·Age: 65+

Code: NCT06377852·Phase 3·Recruiting

Apply to this trial

TReatment of ADC-Refractory Breast CancEr With Dato-DXd or T-DXd: TRADE DXd

for Breast Cancer

11 locations incl. Birmingham

Sponsor: Ana C Garrido-Castro, MD

Sex: All·Age: 18+

Code: NCT06533826·Phase 2·Recruiting

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Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

for Solid Tumor, Adult

19 locations incl. Duarte

Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All·Age: 18+

Code: NCT06625775·Phase 1·Recruiting

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Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

for Cardiovascular Diseases

37 locations incl. Little Rock

Sponsor: BrioHealth Solutions, Inc.

Sex: All·Age: 18 - 100

Code: NCT06310031·Recruiting

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A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer

for Advanced Breast Cancer

35 locations incl. Springdale

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06638307·Phase 1·Recruiting

Apply to this trial

A Study of DM001 in Patients With Advanced Solid Tumors

for Breast Neoplasms

2 locations incl. Nashville

Sponsor: Xadcera Biopharmaceutical (Suzhou) Co., Ltd.

Sex: All·Age: 18+

Code: NCT06475937·Phase 1·Recruiting

Apply to this trial

Sensorimotor and Psychosocial Trajectories in Adolescents With Tic Disorder

for Tourette Syndrome

1 location in Nashvile

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 11 - 17·Accepts healthy volunteers

Code: NCT06576726·Recruiting

Apply to this trial

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

for Healthy Volunteers, Pulmonary Arterial Hypertension

19 locations incl. Scottsdale

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06649110·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Antitumor Activity of ALK201 in Participants With Advanced Solid Tumors

for Advanced Cancer

4 locations incl. Denver

Sponsor: Shanghai Allink Biotherapeutics Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT06656390·Phase 1, Phase 2·Recruiting

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Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

for Classic Follicular Lymphoma

Drug: Mosunetuzumab

267 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06337318·Phase 3·Recruiting

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The ADAPT Trial: Adapting Evidence-Based Obesity Interventions in Community Settings

for Childhood Obesity

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 6 - 12·Accepts healthy volunteers

Code: NCT06546696·Recruiting

Apply to this trial

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

for Basal Ganglia Germinoma

92 locations incl. Mobile

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT06368817·Phase 2·Recruiting

Apply to this trial

Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age

for Amblyopia

58 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 8 - 12

Code: NCT06524882·Phase 3·Recruiting

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FIH Trial of VERT-002 in Patients With Locally Advanced or Metastatic Solid Tumors With MET Alterations

for Solid Tumor

3 locations incl. Washington D.C.

Sponsor: Pierre Fabre Medicament

Sex: All·Age: 18+

Code: NCT06669117·Phase 1, Phase 2·Recruiting

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ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)

for Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome

8 locations incl. San Diego

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: Male·Age: 2 - 65

Code: NCT06430385·Phase 1, Phase 2·Recruiting

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Open-Label Extension Study of Setmelanotide

for Obesity Associated With Defects in Leptin-melanocortin Pathway

13 locations incl. Scottsdale

Sponsor: Rhythm Pharmaceuticals, Inc.

Sex: All·Age: 2+

Code: NCT06596135·Phase 3·Enrolling By Invitation

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

for Carcinoma, Non-Small-Cell Lung

Drug: Intismeran autogene

48 locations incl. Gilbert

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06623422·Phase 3·Recruiting

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Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

for Long COVID

Drug: Baricitinib

17 locations incl. Tucson

Sponsor: Wes Ely

Sex: All·Age: 18+

Code: NCT06631287·Phase 3·Recruiting

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A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

for Colorectal Neoplasms

Drug: Amivantamab

79 locations incl. Gilbert

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06662786·Phase 3·Recruiting

Apply to this trial

J-Valve Transfemoral Pivotal Study

for Aortic Valve Regurgitation

34 locations incl. Scottsdale

Sponsor: JC Medical, Inc., an affiliate of Edwards Lifesciences LLC

Sex: All·Age: 18+

Code: NCT06455787·Recruiting

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A Study of the Safety and Efficacy of Prime Editing (PM359) in Participants With p47phox Autosomal Recessive Chronic Granulomatous Disease (CGD )

for Chronic Granulomatous Disease

3 locations incl. Los Angeles

Sponsor: Prime Medicine, Inc.

Sex: All·Age: 6+

Code: NCT06559176·Phase 1, Phase 2·Enrolling By Invitation

CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies

for Hematologic Malignancy

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT06326463·Phase 1·Recruiting

Apply to this trial

A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

76 locations incl. Mesa

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting

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Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

for Arthritis, Psoriatic

44 locations incl. Avondale

Sponsor: MoonLake Immunotherapeutics AG

Sex: All·Age: 18+

Code: NCT06641089·Phase 3·Recruiting

Apply to this trial

A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

for Leukemia, Juvenile Myelomonocytic

Drug: Trametinib

19 locations incl. Phoenix

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 Month - 21

Code: NCT05849662·Phase 1, Phase 2·Recruiting

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A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults

for Episodic Migraine

71 locations incl. Birmingham

Sponsor: Ipsen

Sex: All·Age: 18 - 80

Code: NCT06625060·Phase 2·Recruiting

Apply to this trial

A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis

for Diffuse Cutaneous Systemic Sclerosis

Drug: Ianalumab

17 locations incl. Mesa

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 70

Code: NCT06470048·Phase 2·Recruiting

Apply to this trial

A First-in-human Study of KK8123 in Adults With X-linked Hypophosphatemia

for X-linked Hypophosphatemia

5 locations incl. San Francisco

Sponsor: Kyowa Kirin Co., Ltd.

Sex: All·Age: 18 - 65

Code: NCT06525636·Phase 1, Phase 2·Recruiting

Apply to this trial

Gluten Technology and Education for Celiac Health

for Celiac Disease

4 locations incl. Chicago

Sponsor: Columbia University

Sex: All·Age: 18 - 75

Code: NCT06059716·Recruiting

Apply to this trial

Phase 1 Study of ACR-2316 in Specific Advanced Solid Tumors

for Specific Advanced Solid Tumors

15 locations incl. Phoenix

Sponsor: Acrivon Therapeutics

Sex: All·Age: 18+

Code: NCT06667141·Phase 1·Recruiting

Apply to this trial

A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

for Metastatic Non-small Cell Lung Cancer

Drug: Osimertinib

34 locations incl. Fayetteville

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06417814·Phase 3·Recruiting

Apply to this trial

Study to Assess Real-world Effectiveness of Belimumab for Treatment of Adults With LN

for Lupus Nephritis

4 locations incl. Baltimore

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06527872·Recruiting

Apply to this trial

Evaluation of TL-925 for the Treatment of Allergic Conjunctivitis

for Allergic Conjunctivitis

1 location in Memphis

Sponsor: Telios Pharma, Inc.

Sex: All·Age: 18+

Code: NCT06686472·Phase 2·Recruiting

Apply to this trial

REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities

for Coronary Artery Disease

18 locations incl. Glendale

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 18+

Code: NCT06399705·Phase 3·Recruiting

Apply to this trial

A Trial to Test if TEV-56286 is Effective for Treatment of Participants With Multiple System Atrophy

for Multiple System Atrophy

19 locations incl. La Jolla

Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All·Age: 30 - 75

Code: NCT06568237·Phase 2·Recruiting

Apply to this trial

A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer

for Breast Cancer

13 locations incl. Tucson

Sponsor: Processa Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06568692·Phase 2·Recruiting

Apply to this trial

A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer

for Non-muscle Invasive Bladder Cancer With Carcinoma in Situ

Drug: Nadofaragene Firadenovec

38 locations incl. Tucson

Sponsor: Ferring Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06545955·Phase 3·Recruiting

Apply to this trial

Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy

for Diabetic Peripheral Neuropathic Pain

76 locations incl. Anniston

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 80

Code: NCT06628908·Phase 3·Recruiting

Apply to this trial

Social Needs App for Oncology Patients Phase II

for Cancer

3 locations incl. Baltimore

Sponsor: JHSPH Center for Clinical Trials

Sex: All·Age: 18+

Code: NCT06688513·Enrolling By Invitation

A Study of GSK5764227 in Participants With Advanced Solid Tumors (EMBOLD)

for Neoplasms

15 locations incl. Stanford

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06551142·Phase 1·Recruiting

Apply to this trial