Paid Clinical Trials in Tennessee

Tennessee has 2,156 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

Filter results

Filter results

State

City

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

2,156 clinical trials

↓ Download CSV

A Study to Investigate Subcutaneous Isatuximab in Combination With Weekly Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma

for Plasma Cell Myeloma Refractory

34 locations incl. Phoenix

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06356571·Phase 2·Recruiting

Apply to this trial

DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

for Glioblastoma (GBM)

16 locations incl. Gilbert

Sponsor: Diakonos Oncology Corporation

Sex: All·Age: 18+

Code: NCT06805305·Phase 2·Recruiting

Apply to this trial

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohns Disease

Drug: Afimkibart

92 locations incl. Dothan

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06819878·Phase 3·Recruiting

Apply to this trial

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

for Triple Negative Breast Neoplasms

38 locations incl. Mobile

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06841354·Phase 3·Recruiting

Apply to this trial

Barriers and Facilitators to OTC Hearing Aids Success

for Hearing Loss, Sensorineural

2 locations incl. Iowa City

Sponsor: Yu-Hsiang Wu

Sex: All·Age: 18 - 89

Code: NCT06499805·Recruiting

Apply to this trial

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

for Clear Cell Renal Cell Carcinoma

414 locations incl. Phoenix

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06661720·Phase 3·Recruiting

Apply to this trial

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

for Heart Failure

Drug: Dapagliflozin

194 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT06677060·Phase 3·Recruiting

Apply to this trial

A Study to Assess a New Medicine Called IPN01195 When Administered Alone in Adults With Advanced Solid Tumours

for Advanced Solid Tumor

5 locations incl. Grand Rapids

Sponsor: Ipsen

Sex: All·Age: 18+

Code: NCT06833008·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

55 locations incl. Birmingham

Sponsor: Celgene

Sex: Male·Age: 18+

Code: NCT06764485·Phase 3·Recruiting

Apply to this trial

A Phase 1 Study of STX-0712 in Patients With Advanced Hematological Malignancies (CMML and AML)

for Chronic Myelomonocytic Leukemia

7 locations incl. Stanford

Sponsor: Solu Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT06950034·Phase 1·Recruiting

Apply to this trial

Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant Recipients

for Lung Transplant

11 locations incl. Los Angeles

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12+

Code: NCT06476132·Phase 2·Recruiting

Apply to this trial

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

for Fallopian Tube Endometrioid Adenocarcinoma

Drug: Bevacizumab

658 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06580314·Phase 3·Recruiting

Apply to this trial

A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

for Metastatic Colorectal Cancer

14 locations incl. Scottsdale

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06792695·Phase 2·Recruiting

Apply to this trial

A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine

for Menstrual Migraine

Drug: Rimegepant

32 locations incl. Phoenix

Sponsor: Pfizer

Sex: Female·Age: 18 - 45

Code: NCT06641466·Phase 3·Recruiting

Apply to this trial

BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

for Limited Stage Small Cell Lung Cancer

Drug: Durvalumab

33 locations incl. Daphne

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 18+

Code: NCT06773910·Phase 2·Recruiting

Apply to this trial

A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)

for Urinary Bladder Neoplasms

Drug: Intismeran autogene

20 locations incl. Bakersfield

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06833073·Phase 2·Recruiting

Apply to this trial

A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel

for Unresectable Melanoma

Drug: Lifileucel

3 locations incl. Denver

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT06940739·Phase 1, Phase 2·Recruiting

Apply to this trial

Alleviant ALLAY-HFrEF Study

for Heart Failure

35 locations incl. Los Angeles

Sponsor: Alleviant Medical, Inc.

Sex: All·Age: 18+

Code: NCT06812533·Enrolling By Invitation

Continuous Glucose Monitoring for Outpatient Diabetes Management After Hospital Discharge

for Type 2 Diabetes Mellitus (T2DM)

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06852950·Recruiting

Apply to this trial

A Study of VRC07-523LS, PGT121.414.LS, and PGDM1400LS Broadly Neutralizing Monoclonal Antibodies Given Intravenously in Adult Participants Without HIV

for HIV

13 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06812494·Phase 2·Recruiting

Apply to this trial

Embryonal Tumor With Multilayered Rosettes

for Embryonal Tumor With Multilayered Rosettes

7 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: All ages

Code: NCT06861244·Phase 2·Recruiting

Apply to this trial

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

for Psoriatic Arthritis

Drug: Tirzepatide

53 locations incl. Avondale

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06864026·Phase 4·Recruiting

Apply to this trial

Bio-Integrative, Fiber-Reinforced Kneebar for Treating Subchondral Insufficiency of the Knee

for Subchondral Insufficiency Fracture

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 75

Code: NCT06423378·Phase 2·Enrolling By Invitation

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

for Mantle Cell Lymphoma

Drug: Sonrotoclax

37 locations incl. Birmingham

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06742996·Phase 3·Recruiting

Apply to this trial

A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

for B-Cell Non-Hodgkins Lymphoma

Drug: Glofitamab

33 locations incl. Anchorage

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06806033·Phase 2·Recruiting

Apply to this trial

Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease

for APOL1-Mediated Kidney Disease

67 locations incl. Alabaster

Sponsor: AstraZeneca

Sex: All·Age: 18 - 65

Code: NCT06824987·Phase 2·Recruiting

Apply to this trial

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

for Cancer

12 locations incl. Orlando

Sponsor: Alterome Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06835569·Phase 1·Recruiting

Apply to this trial

INHANCE Stemless Reverse Shoulder IDE

for Arthroplasty

19 locations incl. Irvine

Sponsor: DePuy Orthopaedics

Sex: All·Age: 22+

Code: NCT06323980·Recruiting

Apply to this trial

An Ophthalmic Safety Study in Patients With Breast Cancer

for Ophthalmic Safety in Patients With Breast Cancer

12 locations incl. La Jolla

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06767462·Recruiting

Apply to this trial

A Study of TYRA-300 in Children With Achondroplasia: BEACH301

for Achondroplasia

11 locations incl. Torrance

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 3 - 10

Code: NCT06842355·Phase 2·Recruiting

Apply to this trial

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines

for Psoriatic Arthritis

Drug: Zasocitinib

54 locations incl. Chandler

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06671483·Phase 3·Recruiting

Apply to this trial

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

for Chronic Kidney Disease and Hypertension

Drug: Dapagliflozin

132 locations incl. Fairhope

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06742723·Phase 3·Recruiting

Apply to this trial

A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy

for Multiple System Atrophy

6 locations incl. Los Angeles

Sponsor: Dasher Neuroscience Inc.

Sex: All·Age: 30+

Code: NCT06848231·Phase 2·Recruiting

Apply to this trial

A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

for HER2-positive Gastric Cancer

Drug: Rilvegostomig

53 locations incl. Anchorage

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06764875·Phase 3·Recruiting

Apply to this trial

Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0

for Acute Kidney Injury

50 locations incl. Birmingham

Sponsor: Indiana University

Sex: All·Age: 0 Minutes - 2 Weeks

Code: NCT06823115·Enrolling By Invitation

Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients

for Orthopaedic Trauma

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 70

Code: NCT06201676·Phase 4·Recruiting

Apply to this trial

Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent Myelofibrosis

for Primary Myelofibrosis

5 locations incl. Ann Arbor

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06517875·Phase 2·Recruiting

Apply to this trial

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

for Advanced Solid Tumor

21 locations incl. Scottsdale

Sponsor: Clasp Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06778863·Phase 1·Recruiting

Apply to this trial

Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

for Hematopoietic and Lymphatic System Neoplasm

190 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: Female·Age: Up to 39

Code: NCT06513962·Phase 3·Recruiting

Apply to this trial

Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer

for Gastric Cancer

18 locations incl. New Haven

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06731478·Phase 3·Recruiting

Apply to this trial