Paid Clinical Trials in South Carolina

South Carolina has 1,276 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,276 clinical trials

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Galvanize Prospective/Retrospective Pulsed Electric Field Device Registry

for Soft Tissue Lesion

10 locations incl. Gilbert

Sponsor: Galvanize Therapeutics, Inc.

Sex: All·Age: 18 - 100

Code: NCT05851430·Recruiting

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Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

for Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

149 locations incl. Gilbert

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06532279·Phase 2·Recruiting

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Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1)

for Hidradenitis Suppurativa

Drug: Ruxolitinib

59 locations incl. Phoenix

Sponsor: Incyte Corporation

Sex: All·Age: 12+

Code: NCT06959225·Phase 3·Recruiting

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Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)

for Pulmonary Disease, Chronic Obstructive

Drug: Depemokimab

55 locations incl. Sheffield

Sponsor: GlaxoSmithKline

Sex: All·Age: 40 - 80

Code: NCT06961214·Phase 3·Recruiting

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A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio

for Geographic Atrophy Secondary to Age-related Macular Degeneration

Drug: Pegcetacoplan

68 locations incl. Gilbert

Sponsor: Apellis Pharmaceuticals, Inc.

Sex: All·Age: 60+

Code: NCT07215390·Phase 2·Recruiting

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab

for Acute Respiratory Distress Syndrome (ARDS)

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701682·Phase 2·Recruiting

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Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA -1)

for Pulmonary Disease, Chronic Obstructive

Drug: Depemokimab

4 locations incl. Loxahatchee Groves

Sponsor: GlaxoSmithKline

Sex: All·Age: 40 - 80

Code: NCT06959095·Phase 3·Recruiting

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A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

for Rheumatoid Arthritis

52 locations incl. Peoria

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06972446·Phase 2·Recruiting

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Digital Wellness Nurse - FIT Families: Virtual Family Intervention for Adolescent Obesity

for Obese Children and Adolescents

1 location in Charleston

Sponsor: Machine and Human Interaction

Sex: All·Age: 12 - 17

Code: NCT07087808·Recruiting

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A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

for Prostate Cancer

10 locations incl. Huntsville

Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male·Age: 18+

Code: NCT07005154·Phase 2·Recruiting

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A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

for Parkinsons Disease (PD)

31 locations incl. Sun City

Sponsor: BlueRock Therapeutics

Sex: All·Age: 45 - 75

Code: NCT06944522·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic Dermatitis

for Atopic Dermatitis

16 locations incl. Lancaster

Sponsor: Inmagene LLC

Sex: All·Age: 18 - 74

Code: NCT07037901·Phase 2·Recruiting

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An Observational Study of Individuals With Isolated Dystonia

for Isolated/Primary Dystonia That Affects More Than One Region of the Body

29 locations incl. Scottsdale

Sponsor: Vima Therapeutics

Sex: All·Age: 12 - 65

Code: NCT07111663·Recruiting

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Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

for Myelodysplastic Syndrome

138 locations incl. Berkeley

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06577441·Phase 2·Recruiting

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Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2)

for Hidradenitis Suppurativa

Drug: Ruxolitinib

67 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 12+

Code: NCT06958211·Phase 3·Recruiting

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Contour Neurovascular System™ ContiNued Access Investigational Device EXempTion (IDE) Trial (NEXT Trial)

for Cerebral Aneurysms

9 locations incl. Park Ridge

Sponsor: Cerus Endovascular, Inc.

Sex: All·Age: 18 - 75

Code: NCT06693011·Recruiting

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

for Acute Respiratory Distress Syndrome (ARDS)

Drug: Cohort B: paridiprubart

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701669·Phase 2·Recruiting

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)

for Acute Respiratory Distress Syndrome (ARDS)

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06703073·Phase 2·Recruiting

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The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

for Bronchiectasis

80 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 12+

Code: NCT06872892·Phase 3·Recruiting

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Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

for Acute Leukemia of Ambiguous Lineage

Drug: Venetoclax

112 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 365 Days

Code: NCT06317662·Phase 2·Recruiting

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Virtuos Bone Graft in Lumbar Fusion

for Degenerative Disc Disease

9 locations incl. South Bend

Sponsor: Orthofix Inc.

Sex: All·Age: 18+

Code: NCT06686017·Enrolling By Invitation

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

for Head and Neck Squamous Cell Carcinoma

200 locations incl. Gilbert

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06992427·Phase 3·Recruiting

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A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

for Cardiovascular Disease

Drug: AZD0780

315 locations incl. Athens

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07000357·Phase 3·Recruiting

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Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System

for Persistent Atrial Fibrillation

32 locations incl. Mobile

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT06735534·Recruiting

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A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

for Triple Negative Breast Cancer

10 locations incl. Denver

Sponsor: Dren Bio

Sex: All·Age: 18+

Code: NCT06999187·Phase 1·Recruiting

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Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin

for Ototoxicity, Drug-Induced

7 locations incl. San Francisco

Sponsor: Kevin Winthrop

Sex: All·Age: 18 - 80

Code: NCT05730283·Phase 2·Recruiting

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Physiological Responses to Heat Stress During High-risk Events

for Thermoregulation

2 locations incl. Fort Novosel

Sponsor: United States Army Research Institute of Environmental Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06907225·Recruiting

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A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

for B Acute Lymphoblastic Leukemia

137 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 366 Days - 46

Code: NCT06124157·Phase 2·Recruiting

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Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

for Prostate Cancer (Adenocarcinoma)

350 locations incl. Anchorage

Sponsor: Canadian Cancer Trials Group

Sex: Male·Age: 18+

Code: NCT06592924·Phase 3·Recruiting

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STimulation to Activate RespIration

for ARDS (Moderate or Severe)

5 locations incl. La Jolla

Sponsor: Lungpacer Medical Inc.

Sex: All·Age: 18+

Code: NCT06832306·Recruiting

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Study of BLU-808 in Chronic Inducible Urticaria (CIndU) and Chronic Spontaneous Urticaria (CSU)

for Chronic Inducible Urticaria

27 locations incl. Birmingham

Sponsor: Blueprint Medicines Corporation

Sex: All·Age: 18+

Code: NCT06931405·Phase 2·Recruiting

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MEP Up-conditioning to Target Corticospinal Plasticity

for Spinal Cord Injury

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06989905·EARLY_Phase 1·Recruiting

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Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis

for Generalized Myasthenia Gravis

Drug: IMVT-1402

46 locations incl. Huntsville

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 80

Code: NCT07039916·Phase 3·Recruiting

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Small Cell Lung Cancer Community Engagement to Eliminate Research Discepancies

for Small-cell Lung Cancer

52 locations incl. Multiple Locations

Sponsor: Addario Lung Cancer Medical Institute

Sex: All·Age: 18+

Code: NCT06486428·Recruiting

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Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Drug: Cemiplimab

386 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06616584·Phase 2, Phase 3·Recruiting

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A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Idiopathic Hypersomnia

for Idiopathic Hypersomnia

Drug: ALKS 2680

32 locations incl. Cullman

Sponsor: Alkermes, Inc.

Sex: All·Age: 18 - 70

Code: NCT06843590·Phase 2·Recruiting

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A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

for Heart Failure

Drug: Empagliflozin

105 locations incl. Mobile

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06935370·Phase 3·Recruiting

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A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

for Asthma

Drug: PF-07275315

36 locations incl. Mobile

Sponsor: Pfizer

Sex: All·Age: 18 - 70

Code: NCT06977581·Phase 2·Recruiting

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Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation

for Delayed Graft Function

32 locations incl. Phoenix

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06830798·Phase 3·Recruiting

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A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

for Lower Extremity Acute Limb Ischemia

31 locations incl. Scottsdale

Sponsor: Penumbra Inc.

Sex: All·Age: 18+

Code: NCT06747117·Recruiting

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