Paid Clinical Trials in San Francisco, CA

As of June 2026, 1,434 paid clinical trials are recruiting in San Francisco, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,434 clinical trials

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A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

for B Acute Lymphoblastic Leukemia Associated With Down Syndrome

69 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 6 - 39

Code: NCT05702645·Recruiting

Apply to this trial

Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)

for Soft Tissue Sarcoma

26 locations incl. Phoenix

Sponsor: Polaris Group

Sex: All·Age: 18 - 99

Code: NCT05712694·Phase 3·Recruiting

Apply to this trial

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

for Heart Failure NYHA Class II

47 locations incl. Phoenix

Sponsor: Endotronix, Inc.

Sex: All·Age: 18+

Code: NCT05934487·Recruiting

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The Heart Health After Cardiac Treatment Study

for Cardiac Rehabilitation

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT07158515·Recruiting

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Prehospital Analgesia INtervention Trial (PAIN)

for Traumatic Injury

11 locations incl. San Diego

Sponsor: Jason Sperry

Sex: All·Age: 18+

Code: NCT05437575·Phase 3·Recruiting

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Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

for Anatomic Stage II Breast Cancer AJCC v8

Drug: Durvalumab

536 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06058377·Phase 3·Recruiting

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ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

for Aortic Valve Insufficiency

32 locations incl. Newport Beach

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT05172973·Recruiting

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Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations

for Locally Advanced Cholangiocarcinoma

4 locations incl. San Francisco

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06160752·Phase 1·Recruiting

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Comprehensive HHT Outcomes Registry of the United States (CHORUS)

for Hereditary Hemorrhagic Telangiectasia

16 locations incl. Birmingham

Sponsor: Cure HHT

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06259292·Recruiting

Apply to this trial

Trial of Ixazomib for Kaposi Sarcoma

for Kaposi Sarcoma

11 locations incl. San Diego

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 18+

Code: NCT04305691·Phase 2·Recruiting

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Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors

for Cancer

17 locations incl. San Francisco

Sponsor: MBrace Therapeutics

Sex: All·Age: 18+

Code: NCT06014658·Phase 1, Phase 2·Recruiting

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Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

for Single Ventricle Heart Disease

37 locations incl. Phoenix

Sponsor: Mezzion Pharma Co. Ltd

Sex: All·Age: 12 - 18

Code: NCT05918211·Phase 3·Recruiting

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MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation

for Myocardial Infarction

5 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT05933083·Recruiting

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Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future

for LVAD

7 locations incl. San Francisco

Sponsor: International Consortium of Circulatory Assist Clinicians

Sex: All·Age: 18 - 100

Code: NCT06039176·Recruiting

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Valacyclovir in Pain Management of Acute Apical Abscesses

for Acute Apical Abscess

Drug: Valacyclovir

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT05266040·Phase 2·Recruiting

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Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas

for Ewing Sarcoma

Drug: Cabozantinib

4 locations incl. San Francisco

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 5 - 40

Code: NCT06156410·Phase 1·Recruiting

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Fecal Microbiota Transplant National Registry

for Fecal Microbiota Transplant

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: All ages

Code: NCT06262451·Enrolling By Invitation

An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplant

for Chronic Kidney Disease (CKD)

9 locations incl. Los Angeles

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 70

Code: NCT05106387·Recruiting

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

1208 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting

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A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC

for Adenocarcinoma, Pancreatic Ductal

Drug: Atezolizumab

32 locations incl. Los Angeles

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT05968326·Phase 2·Recruiting

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PROmOting Gynecologic Cancer Patients With Frailty to Achieve Functional Recovery

for Malignant Female Reproductive System Neoplasm

2 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: Female·Age: 18+

Code: NCT06089083·Recruiting

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A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer

for Metastatic Breast Cancer

12 locations incl. Birmingham

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06099769·Phase 2·Recruiting

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PRIMARY Ancillary Substudy

for Mitral Valve Prolapse

16 locations incl. Los Angeles

Sponsor: Annetine Gelijns

Sex: All·Age: 60+

Code: NCT07103733·Recruiting

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DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers

for Small Cell Lung Carcinoma

16 locations incl. Mobile

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT05882058·Phase 2·Recruiting

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Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS

for Acute Coronary Syndrome

178 locations incl. Alexander City

Sponsor: DalCor Pharmaceuticals

Sex: All·Age: 45+

Code: NCT05918861·Phase 3·Recruiting

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Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

for IC-MPGN

Drug: Iptacopan

22 locations incl. Los Angeles

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 60

Code: NCT05755386·Phase 3·Recruiting

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PrEPsmart 2-1-1 Pilot

for HIV-1-infection

1 location in San Francisco

Sponsor: Public Health Foundation Enterprises, Inc.

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT06631365·Phase 2·Recruiting

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Correction of Psoriatic T Cell Signatures by Deucravacitinib

for Psoriasis Vulgaris

Drug: Deucravacitinib

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 75

Code: NCT05858645·Phase 4·Recruiting

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Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan

for Acute Suicidal Depression (ASD)

9 locations incl. San Francisco

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 90

Code: NCT06034821·Phase 4·Enrolling By Invitation

Focal Cerebral Arteriopathy Steroid Trial

for Pediatric Stroke

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 1 - 18

Code: NCT06040255·Phase 4·Enrolling By Invitation

Preschool Hearing Screening

for Hearing Loss

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 6

Code: NCT06058767·Recruiting

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Investigating the Use of Intravenous Tranexamic Acid in Gender Affirming Mastectomy

for Postoperative Hematoma

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT05794321·Phase 2·Recruiting

Apply to this trial

Recovery Trajectory for Coma and Disorders of Consciousness

for Coma

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT07614074·Recruiting

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MCT for the Harvard/UCSF ROBIN Center

for Glioma, Childhood Brainstem

2 locations incl. San Francisco

Sponsor: Brigham and Women's Hospital

Sex: All·Age: All ages

Code: NCT06000787·Recruiting

Apply to this trial

Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens

for Myopia

14 locations incl. Oakland

Sponsor: SightGlass Vision, Inc.

Sex: All·Age: 6 - 8·Accepts healthy volunteers

Code: NCT06034327·Recruiting

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Genomic Sequencing for Evaluation of Fetal Structural Anomalies

for Fetal Structural Anomalies

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT06054230·Enrolling By Invitation

Gene Therapy Trial for Otoferlin Gene-mediated Hearing Loss

for Sensorineural Hearing Loss, Bilateral

6 locations incl. San Francisco

Sponsor: Akouos, Inc.

Sex: All·Age: All ages

Code: NCT05821959·Phase 1, Phase 2·Recruiting

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

955 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting

Apply to this trial

Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

for Surgery-Complications

20 locations incl. Little Rock

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT05991453·Recruiting

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A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy

for Myositis

18 locations incl. Phoenix

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT05979441·Phase 3·Enrolling By Invitation