Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancerfor Breast Neoplasms11 locations incl. FullertonSponsor: Stemline Therapeutics, Inc.Sex: All·Age: 18+Code: NCT05386108·Phase 1, Phase 2·RecruitingApply to this trial
Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Metsfor Brain Tumor8 locations incl. PhoenixSponsor: InSightecSex: All·Age: 18 - 100Code: NCT05317858·Phase 3·RecruitingApply to this trial
Immuno-PRISM (PRecision Intervention Smoldering Myeloma)for High-risk Smoldering Multiple Myeloma3 locations incl. DenverSponsor: Irene Ghobrial, MDSex: All·Age: 18+Code: NCT05469893·Phase 2·RecruitingApply to this trial
Brain Injury Education and Outpatient Navigation-1stBIENfor Brain Injuries, Traumatic6 locations incl. Colorado SpringsSponsor: Seattle Children's HospitalSex: All·Age: 3+Code: NCT05261477·RecruitingApply to this trial
Bringing Weight Management Into the Primary Care Pediatric Practicefor Obesity, Childhood2 locations incl. PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 1 Month - 21Code: NCT05950620·RecruitingApply to this trial
Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Studyfor CADASIL12 locations incl. Los AngelesSponsor: University of Wisconsin, MadisonSex: All·Age: 18+·Accepts healthy volunteersCode: NCT05677880·RecruitingApply to this trial
Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemiafor Relapsed Adult AML20 locations incl. BirminghamSponsor: Massachusetts General HospitalSex: All·Age: 18 - 120·Accepts healthy volunteersCode: NCT05237258·RecruitingApply to this trial
Single-dose Intravenous Iron Therapy for Anemia After Orthopaedic Traumafor Acute Blood Loss Anemia1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 18 - 89Code: NCT05292001·Phase 4·RecruitingApply to this trial
Food and Circadian Timingfor Diet, High-Fat1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 18 - 40·Accepts healthy volunteersCode: NCT04743271·RecruitingApply to this trial
Caloric Restriction and Activity to Reduce Chemoresistance in B-ALLfor B-cell Acute Lymphoblastic Leukemia20 locations incl. Los AngelesSponsor: Etan OrgelSex: All·Age: 10 - 25Code: NCT05082519·Phase 2·RecruitingApply to this trial
Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphomafor Relapsed or Refractory T Cell Lymphoma20 locations incl. BirminghamSponsor: Ono Pharmaceutical Co., Ltd.Sex: All·Age: 18+Code: NCT05079282·Phase 1·RecruitingApply to this trial
Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)for Acute Stroke35 locations incl. FairhopeSponsor: DiaMedica Therapeutics IncSex: All·Age: 18 - 90Code: NCT05065216·Phase 2, Phase 3·RecruitingApply to this trial
ConsideRAte Study - Splenic Stimulation for RAfor Rheumatoid Arthritis12 locations incl. AnnistonSponsor: Galvani BioelectronicsSex: All·Age: 22 - 75Code: NCT05003310·RecruitingApply to this trial
Study of OCTAPLEX in Patients With Acute Major Bleeding on DOAC Therapy With Factor Xa Inhibitorfor Acute Major Bleeding10 locations incl. TorranceSponsor: OctapharmaSex: All·Age: 18+Code: NCT04867837·Phase 3·RecruitingApply to this trial
Study in Parkinson Disease of Exercisefor Parkinson Disease24 locations incl. BirminghamSponsor: Northwestern UniversitySex: All·Age: 40 - 80Code: NCT04284436·RecruitingApply to this trial
Trial of Therapeutic Hypothermia in Patients With ARDSfor Respiratory Distress Syndrome, Adult19 locations incl. Los AngelesSponsor: University of Maryland, BaltimoreSex: All·Age: 18 - 85Code: NCT04545424·Phase 2·RecruitingApply to this trial
Trial-Ready Cohort-Down Syndrome (TRC-DS)for Down Syndrome18 locations incl. PhoenixSponsor: University of Southern CaliforniaSex: All·Age: 25 - 55Code: NCT04165109·RecruitingApply to this trial
Treatment of the Biceps With Concomitant Supraspinatus Tearsfor Supraspinatus Tear2 locations incl. Ann ArborSponsor: La Tour HospitalSex: All·Age: 50 - 80Code: NCT05660031·RecruitingApply to this trial
Hypertonic Saline for MACfor Nontuberculous Mycobacterial Lung Disease2 locations incl. New YorkSponsor: Oregon Health and Science UniversitySex: All·Age: 18+Code: NCT04921943·Phase 4·RecruitingApply to this trial
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)for Pulmonary Arterial Hypertension27 locations incl. PhoenixSponsor: Merck Sharp & Dohme LLCSex: All·Age: 18+Code: NCT07218029·Phase 3·RecruitingApply to this trial
Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCMfor Symptomatic Hypertrophic Cardiomyopathy (HCM)Drug: Aficamten52 locations incl. BirminghamSponsor: CytokineticsSex: All·Age: 18 - 85Code: NCT04848506·Phase 2, Phase 3·Enrolling By Invitation
Directional Versus Nondirectional DBS for ETfor Essential Tremor1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 18 - 80Code: NCT04828798·RecruitingApply to this trial
The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).for Mitral Annular Calcification16 locations incl. GilbertSponsor: Mayra GuerreroSex: All·Age: 18+Code: NCT04408430·RecruitingApply to this trial
Fenofibrate for Prevention of DR Worseningfor Diabetic Retinopathy66 locations incl. GlendaleSponsor: Jaeb Center for Health ResearchSex: All·Age: 18 - 80Code: NCT04661358·Phase 3·RecruitingApply to this trial
Brown Adipose Tissue Activation by Spinal Cord Stimulationfor Pain, Back1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 21 - 70Code: NCT04326192·RecruitingApply to this trial
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumorsfor Advanced Cancer40 locations incl. BirminghamSponsor: Artios Pharma LtdSex: All·Age: 18+Code: NCT04657068·Phase 1, Phase 2·RecruitingApply to this trial
The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot Studyfor Mitral Valve Insufficiency5 locations incl. New YorkSponsor: Half Moon MedicalSex: All·Age: 21 - 95Code: NCT04343313·RecruitingApply to this trial
A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)for Advanced Liver Cancers16 locations incl. Costa MesaSponsor: Hoffmann-La RocheSex: All·Age: 18+Code: NCT04524871·Phase 1, Phase 2·RecruitingApply to this trial
Pancreatic Cancer Early Detection Consortiumfor Pancreas Cancer45 locations incl. PhoenixSponsor: Arbor Research Collaborative for HealthSex: All·Age: 18 - 90·Accepts healthy volunteersCode: NCT04970056·RecruitingApply to this trial
A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Typesfor Solid Tumor24 locations incl. TucsonSponsor: Eisai Inc.Sex: All·Age: 18+Code: NCT04300556·Phase 1, Phase 2·RecruitingApply to this trial
OCT in Fuchs' Dystrophyfor Fuchs Dystrophy1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 18+Code: NCT04258787·RecruitingApply to this trial
Transcranial Magnetic Stimulation in Progressive Supranuclear Palsyfor Palsy Supranuclear1 location in PortlandSponsor: Oregon Health and Science UniversitySex: All·Age: 40 - 85Code: NCT04468932·RecruitingApply to this trial
Prophylactic Reinforcement of Ventral Abdominal Incisions Trialfor Open Midline Laparotomy30 locations incl. PhoenixSponsor: C. R. BardSex: All·Age: 18+Code: NCT03911700·RecruitingApply to this trial
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trialfor Tricuspid Regurgitation73 locations incl. PhoenixSponsor: Edwards LifesciencesSex: All·Age: 18+Code: NCT04097145·RecruitingApply to this trial
Continuation Protocol for ZEN003694 in Patients Experiencing Clinical Benefit While Enrolled in a ZEN003694 Protocolfor mCRPC2 locations incl. San FranciscoSponsor: Zenith EpigeneticsSex: All·Age: 18+Code: NCT04145375·Phase 1, Phase 2·Enrolling By Invitation
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutationfor Acute Myeloid LeukemiaDrug: Revumenib22 locations incl. DuarteSponsor: Syndax PharmaceuticalsSex: All·Age: 30 Days+Code: NCT04065399·Phase 1, Phase 2·RecruitingApply to this trial
Von Willebrand Factor in Pregnancy (VIP) Studyfor Von Willebrand Diseases11 locations incl. AuroraSponsor: University of WashingtonSex: Female·Age: 18+Code: NCT04146376·RecruitingApply to this trial
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extensionfor PAHDrug: Ralinepag48 locations incl. PhoenixSponsor: United TherapeuticsSex: All·Age: 18+Code: NCT03683186·Phase 3·Enrolling By Invitation
Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Studyfor Lower Respiratory Tract Infection49 locations incl. DuarteSponsor: Ansun Biopharma, Inc.Sex: All·Age: All agesCode: NCT03808922·Phase 3·RecruitingApply to this trial
The GBA Multimodal Study in Parkinson's Diseasefor Parkinson Disease2 locations incl. PortlandSponsor: Pacific Parkinson's Research CentreSex: All·Age: 18 - 80Code: NCT04101968·RecruitingApply to this trial