Clinical Trials at Children's Hospital of Pittsburgh of UPMC

As of June 2026, 61 paid clinical trials are recruiting at Children's Hospital of Pittsburgh of UPMC, located at 3705 5TH AVE, PITTSBURGH, PA 15213-2584, phone (412) 692-6207 in Pittsburgh, Pennsylvania. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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61 clinical trials at Children's Hospital of Pittsburgh of UPMC

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HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants

for Hydrocephalus

18 locations incl. Birmingham

Sponsor: University of Utah

Sex: All·Age: 1 Day - 104 Weeks

Code: NCT04177914·Phase 3·Recruiting

Apply to this trial

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

185 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting

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A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

for Low Grade Astrocytoma

Drug: Selumetinib

124 locations incl. Aurora

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 - 21

Code: NCT04166409·Phase 3·Recruiting

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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

203 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting

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Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

for Acute Biphenotypic Leukemia

10 locations incl. Los Angeles

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 6 Months - 26·Accepts healthy volunteers

Code: NCT03779854·Phase 2·Recruiting

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T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

for Sickle Cell Anemia

1 location in Pittsburgh

Sponsor: Paul Szabolcs

Sex: All·Age: 5 - 40

Code: NCT03653338·Phase 1, Phase 2·Recruiting

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Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis

for Systemic Sclerosis

3 locations incl. Pittsburgh

Sponsor: Paul Szabolcs

Sex: All·Age: 8 - 60

Code: NCT03630211·Phase 2·Recruiting

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

152 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting

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Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure

for Idiopathic Pulmonary Fibrosis

2 locations incl. Pittsburgh

Sponsor: Paul Szabolcs

Sex: All·Age: 18 - 60

Code: NCT03500731·Phase 1, Phase 2·Recruiting

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Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

for Recurrent B Acute Lymphoblastic Leukemia

156 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 21

Code: NCT02981628·Phase 2·Recruiting

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Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

for Childhood Extracranial Germ Cell Tumor

566 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT03067181·Phase 3·Recruiting

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Neurogenetics Patient Registry

for Neurogenetic Disorders

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: All ages

Code: NCT02995538·Recruiting

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Exome and Genome Analysis to Elucidate Genetic Etiologies and Population Characteristics in the Plain Community

for Undiagnosed Disease

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: Up to 100·Accepts healthy volunteers

Code: NCT02927158·Recruiting

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National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

for Hypoplastic Left Heart Syndrome (HLHS)

61 locations incl. Birmingham

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 15 Months

Code: NCT02852031·Recruiting

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

245 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting

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A Vaccine Trial for Low Grade Gliomas

for Low Grade Glioma

1 location in Pittsburgh

Sponsor: James Felker

Sex: All·Age: 12 Months - 21

Code: NCT02358187·Phase 2·Recruiting

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Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases

for Severe Combined Immunodeficiency (SCID)

1 location in Pittsburgh

Sponsor: Paul Szabolcs

Sex: All·Age: 5 - 45

Code: NCT01852370·Phase 1, Phase 2·Enrolling By Invitation

Natural History Study of SCID Disorders

for Severe Combined Immunodeficiency (SCID)

39 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: All ages

Code: NCT01186913·Enrolling By Invitation

HCRN Core Data Project: Characterizing Patient Populations in the Hydrocephalus Clinical Research Network (HCRN)

for Pediatric Hydrocephalus

11 locations incl. Birmingham

Sponsor: University of Utah

Sex: All·Age: Up to 18

Code: NCT00670735·Recruiting

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Biomarkers in Transplant Recipients to Improve Outcomes

for Solid Organ Transplantation

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: All ages

Code: NCT01163578·Recruiting

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TrialNet Pathway to Prevention of T1D

for Diabetes Mellitus, Type 1

17 locations incl. Orange

Sponsor: University of South Florida

Sex: All·Age: 2 - 45·Accepts healthy volunteers

Code: NCT00097292·Recruiting

Apply to this trial