Paid Clinical Trials in Philadelphia, PA

As of June 2026, 2,086 paid clinical trials are recruiting in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

Filter results

Filter results

State

City

Facility

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

2,086 clinical trials

↓ Download CSV

Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

for Non Small Cell Lung Cancer

Drug: Osimertinib

146 locations incl. Birmingham

Sponsor: PrECOG, LLC.

Sex: All·Age: 18+

Code: NCT06538038·Recruiting

Apply to this trial

A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma

for Monoclonal Gammopathy of Undetermined Significance (MGUS)

Drug: Linvoseltamab

7 locations incl. Baltimore

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06140524·Phase 2·Recruiting

Apply to this trial

A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF)

for Cystic Fibrosis

4 locations incl. Kansas City

Sponsor: Spirovant Sciences, Inc.

Sex: All·Age: 18 - 65

Code: NCT06526923·Phase 1, Phase 2·Recruiting

Apply to this trial

Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC

for High-Risk Non-Muscle-Invasive Bladder Cancer

65 locations incl. Phoenix

Sponsor: CG Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06567743·Phase 2·Recruiting

Apply to this trial

Surgiphor Us in TSA

for Total Shoulder Arthroplasty

1 location in Philadelphia

Sponsor: Rothman Institute Orthopaedics

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06601803·Phase 4·Enrolling By Invitation

Expanding Liver Transplant Immunosuppression Minimization Via Everolimus

for Liver Transplant

8 locations incl. Phoenix

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06280950·Phase 2·Recruiting

Apply to this trial

Peer Facilitated Waitlist Controlled Transportation Study

for Serious Mental Illness

1 location in Philadelphia

Sponsor: Temple University

Sex: All·Age: 18 - 65

Code: NCT06370767·Recruiting

Apply to this trial

A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B

for Hemophilia B

14 locations incl. Los Angeles

Sponsor: Regeneron Pharmaceuticals

Sex: Male·Age: 2+

Code: NCT06379789·Phase 1, Phase 2·Recruiting

Apply to this trial

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

for Metastatic Dedifferentiated Liposarcoma

245 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06422806·Phase 3·Recruiting

Apply to this trial

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

for Treatment Resistant Depression

24 locations incl. Birmingham

Sponsor: Abbott Medical Devices

Sex: All·Age: 22 - 70

Code: NCT06423430·Recruiting

Apply to this trial

Postpartum Care in the NICU (PeliCaN) Transitions

for Stress Disorders, Post-Traumatic

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 16+

Code: NCT06521398·Recruiting

Apply to this trial

A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis

for Non-cystic Fibrosis Bronchiectasis

29 locations incl. Birmingham

Sponsor: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA

Sex: All·Age: 18 - 80

Code: NCT06559150·Phase 2·Recruiting

Apply to this trial

A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

for Lung Diseases, Interstitial

16 locations incl. Los Angeles

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06572384·Phase 3·Recruiting

Apply to this trial

Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

for Migraine

Drug: Ubrogepant

103 locations incl. Birmingham

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06417775·Phase 3·Recruiting

Apply to this trial

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

for Melanoma

104 locations incl. Chandler

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06246916·Phase 3·Recruiting

Apply to this trial

RevCore for In Stent Thrombosis

for In-stent Thrombosis

16 locations incl. New Haven

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT06394739·Recruiting

Apply to this trial

Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household Smokers Through a Pediatric Care Network

for Smoking

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 18+

Code: NCT06582693·Recruiting

Apply to this trial

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

for NASH - Nonalcoholic Steatohepatitis

Drug: Efruxifermin

168 locations incl. Birmingham

Sponsor: Akero Therapeutics, Inc

Sex: All·Age: 18 - 80

Code: NCT06528314·Phase 3·Recruiting

Apply to this trial

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

for Crohn's Disease

64 locations incl. Dothan

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT06548542·Phase 2·Recruiting

Apply to this trial

A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)

for Pulmonary Hypertension

31 locations incl. Phoenix

Sponsor: Tectonic Therapeutic

Sex: All·Age: 18 - 83

Code: NCT06616974·Phase 2·Recruiting

Apply to this trial

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

for Lung Transplant

18 locations incl. Los Angeles

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06399302·Recruiting

Apply to this trial

First-in-human Study of DB-1419 for Advanced/Metastatic Solid Tumors

for Solid Tumor, Adult

9 locations incl. Los Angeles

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT06554795·Phase 1, Phase 2·Recruiting

Apply to this trial

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes

for Gestational Diabetes

2 locations incl. Rochester

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06419777·Recruiting

Apply to this trial

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes (START 2)

for Gestational Diabetes

2 locations incl. Rochester

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06419803·Recruiting

Apply to this trial

Pilot Trial of the RUBI Program for Autistic Adults

for Autism Spectrum Disorder

3 locations incl. Jupiter

Sponsor: Seattle Children's Hospital

Sex: All·Age: 18+

Code: NCT06593613·Recruiting

Apply to this trial

Timing Impact of Early vs. Late Cranioplasty on Hemicraniectomy Outcomes

for Craniocerebral Trauma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06632587·Recruiting

Apply to this trial

Taking Action for College Students

for Major Depressive Disorder

1 location in Philadelphia

Sponsor: Temple University

Sex: All·Age: 18+

Code: NCT06700902·Recruiting

Apply to this trial

CRS Questionnaire Validation Project

for Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps

5 locations incl. Santa Monica

Sponsor: The European Forum for Research and Education in Allergy and Airway Diseases

Sex: All·Age: 18+

Code: NCT06970977·Recruiting

Apply to this trial

MILC: A Comprehensive Mobile Application That Addresses the Breastfeeding Challenges of Low-income Hispanic Mothers

for Breastfeeding, Exclusive

3 locations incl. Farmington

Sponsor: Benten Technologies, Inc.

Sex: Female·Age: 18 - 44·Accepts healthy volunteers

Code: NCT06520696·Not Yet Recruiting

EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

for Kidney Disease, Chronic

Drug: Empagliflozin

41 locations incl. Huntsville

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06531824·Phase 3·Recruiting

Apply to this trial

KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis

for Myasthenia Gravis

8 locations incl. Orange

Sponsor: Kyverna Therapeutics

Sex: All·Age: 18 - 75

Code: NCT06193889·Phase 2, Phase 3·Recruiting

Apply to this trial

Reducing Urban Cervical Cancer Disparities

for Cervical Cancer

3 locations incl. New Brunswick

Sponsor: Fox Chase Cancer Center

Sex: Female·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06416150·Recruiting

Apply to this trial

Trial of Transurethral Bulking Agent Injection Versus Single-Incision Sling for Stress Urinary Incontinence

for Stress Urinary Incontinence

7 locations incl. La Jolla

Sponsor: NICHD Pelvic Floor Disorders Network

Sex: Female·Age: 21+

Code: NCT06480227·Recruiting

Apply to this trial

The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers

for Smoking

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06264154·Recruiting

Apply to this trial

Exparel v Dexamethasone in RCR

for Rotator Cuff Tears

1 location in Philadelphia

Sponsor: Rothman Institute Orthopaedics

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06575010·Phase 4·Enrolling By Invitation

Safety, Pharmacokinetics (PK), and Efficacy of ONC 841 in Advanced Solid Tumors

for Advanced Solid Tumor

8 locations incl. Sacramento

Sponsor: OncoC4, Inc.

Sex: All·Age: 18+

Code: NCT06352359·Phase 1·Recruiting

Apply to this trial

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

for High Grade Glioma

Drug: Ribociclib

11 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT05843253·Phase 2·Recruiting

Apply to this trial

Letrozole and Misoprostol for Early Pregnancy Loss Management

for Early Pregnancy Loss

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 18+

Code: NCT06452719·Phase 2·Recruiting

Apply to this trial

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

for Refractory Differentiated Thyroid Gland Carcinoma

301 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT06475989·Phase 3·Recruiting

Apply to this trial

Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors

for Sub-study 1 Cervical Cancer (Volrustomig Monotherapy)

6 locations incl. Los Angeles

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06535607·Phase 2·Recruiting

Apply to this trial