Paid Clinical Trials in Philadelphia, PA

As of June 2026, 2,086 paid clinical trials are recruiting in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,086 clinical trials

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Improving Heart Health in Individuals With SCI Using Home-Based Virtual Gaming

for Spinal Cord Injuries (SCI)

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18+

Code: NCT06690372·Recruiting

Apply to this trial

Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson Disease

for Overactive Bladder

3 locations incl. Decatur

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07187466·Phase 4·Not Yet Recruiting

Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial to Evaluate the Efficacy and Safety of a GLP-1 Receptor Agonist Semaglutide in U.S. Veterans With Alcohol Use Disorder

for Alcohol Use Disorder

Drug: Semaglutide

1 location in Philadelphia

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07218354·Phase 3·Not Yet Recruiting

COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"

for New Onset Refractory Status Epilepticus

Drug: Tocilizumab

25 locations incl. Phoenix

Sponsor: Yale University

Sex: All·Age: 2+

Code: NCT07281027·Phase 3·Not Yet Recruiting

Effect of cTBS on Startle and TMS-evoked BOLD

for Anxiety

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07415772·Not Yet Recruiting

Validation of NAD+ Measurements for Human Clinical Studies

for Healthy Adults

2 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 110·Accepts healthy volunteers

Code: NCT07416786·Not Yet Recruiting

Efficacy of Integrating Next Generation Sequencing for Treatment of Surgical Site Infection After Fracture Fixation:

for Next Generation Sequencing (NGS)

18 locations incl. Tuscaloosa

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 18 - 84

Code: NCT07458230·Phase 3·Not Yet Recruiting

DaxibotulinumtoxinA for Blepharospasm

for Blepharospasm of Both Eyelids

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07489430·Phase 2·Not Yet Recruiting

Testing an Adaptive Intervention for Peer-Supported Mobile Health for Primary Care Veterans With Psychological Distress

for Psychological Distress

5 locations incl. Palo Alto

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07507747·Not Yet Recruiting

Optimizing Stimulation Parameters for Electroconvulsive Therapy

for Depression - Major Depressive Disorder

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages

Code: NCT07561307·Not Yet Recruiting

A Widely Inclusive, Hybrid-Decentralized Pilot Trial Utilizing β-hydroxy-β-methylbutyrate to Lower IGFBP7 Levels in People With ALS

for Amyotrophic Lateral Sclerosis ALS

2 locations incl. Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT07589764·Phase 1·Not Yet Recruiting

Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use Disorder

for Alcohol Use Disorder

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 21 - 65

Code: NCT06807918·Phase 2, Phase 3·Not Yet Recruiting

An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)

for REM Sleep Behavior Disorder

19 locations incl. Los Angeles

Sponsor: Yale University

Sex: All·Age: 50 - 80

Code: NCT06996652·Phase 2·Not Yet Recruiting

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

for Lymphoma, Non-Hodgkin

23 locations incl. Duarte

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07101328·Phase 1·Not Yet Recruiting

Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up

for Epilepsy

12 locations incl. Phoenix

Sponsor: Epiminder America, Inc.

Sex: All·Age: 18 - 75

Code: NCT07110454·Recruiting

Apply to this trial

A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications

for Parkinson's Disease

26 locations incl. Phoenix

Sponsor: Bayer

Sex: All·Age: 45 - 75

Code: NCT07330258·Recruiting

Apply to this trial

T4/T3 Therapy in Hypothyroidism

for Hypothyroidism Primary

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 70

Code: NCT07424183·Phase 2·Not Yet Recruiting

H&N NEO-COMBAT XL: Neoadjuvant XL-092 (Zanzalintinib) and Pembrolizumab (Keytruda) in Surgically Resectable, HPV Negative Oral Cavity Squamous Cell Carcinoma (OCSCC)

for Oral Cavity Squamous Cell Carcinoma

3 locations incl. Atlanta

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07484139·Phase 2·Not Yet Recruiting

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability Evaluation of CTAP101 Extended-release Capsules in Pediatric Participants

for CKD Stage 3

5 locations incl. Kansas City

Sponsor: OPKO Health, Inc.

Sex: All·Age: 1 Month - 17

Code: NCT07494045·Phase 2·Not Yet Recruiting

Nanozymes in Endodontics

for Apical Periodontitis

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07518901·Phase 4·Not Yet Recruiting

Bilevel Positive Airway Pressure (BPAP) for Severe Asthma

for Pediatric Asthma

3 locations incl. New York

Sponsor: Columbia University

Sex: All·Age: 5 - 17

Code: NCT07582211·Not Yet Recruiting

A Study to Evaluate the Efficacy and Safety of Concomitant Use of Eplontersen and ALXN2220 Compared With Eplontersen and Placebo for Adults Participants With ATTR-CM

for Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

24 locations incl. La Jolla

Sponsor: AstraZeneca

Sex: All·Age: 18 - 85

Code: NCT07608354·Phase 2·Not Yet Recruiting

An International Multicenter, Multivendor Evaluation of the Free-Running Framework for Cardiac Function

for Congenital Heart Diseases

9 locations incl. Los Angeles

Sponsor: Matthias Stuber

Sex: All·Age: All ages

Code: NCT07613398·Not Yet Recruiting

Decision Counseling and Follow-up for Shield+ Patients

for Colo-rectal Cancer

1 location in Philadelphia

Sponsor: Guardant Health, Inc.

Sex: All·Age: 45 - 75·Accepts healthy volunteers

Code: NCT07620535·Not Yet Recruiting

Pilot Deprescribing of Antimuscarinic Overactive Bladder Medications in Parkinson Disease

for Parkinson Disease (PD)

1 location in Philadelphia

Sponsor: Corporal Michael J. Crescenz VA Medical Center

Sex: All·Age: 60+

Code: NCT07627529·Phase 4·Not Yet Recruiting

AUR103 Calcium in Advanced Neuroendocrine Tumours (BHARAT-3 Study)

for Neuroendocrine (NE) Tumors

5 locations incl. Phoenix

Sponsor: Aurigene Discovery Technologies Limited

Sex: All·Age: 18 - 99

Code: NCT07640737·Phase 2·Not Yet Recruiting

A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis

for Systemic Sclerosis

Drug: Nerandomilast

30 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07497087·Phase 3·Not Yet Recruiting

A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection

for HIV-1-infection

10 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 70

Code: NCT06987318·Phase 1·Not Yet Recruiting

A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity

for Obesity

Drug: NNC0662-0419

24 locations incl. Montgomery

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07639021·Phase 2·Not Yet Recruiting

Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease

for Sickle Cell Disease

Drug: Ruxolitinib

4 locations incl. Aurora

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: 12 - 45

Code: NCT07252050·Phase 1, Phase 2·Recruiting

Apply to this trial

Colorectal Cancer Screening Preventive Reminder Ordering AssistanCe Via Texting for Improved Visit Encounters

for Behavior, Health

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07636174·Not Yet Recruiting

Preventive Reminder Ordering AssistanCe Via Texting for Improved Visit Encounters

for Behavior, Health

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07636187·Not Yet Recruiting

Health-E You Efficacy Trial for Male Adolescents

for Sexually Transmitted Diseases

8 locations incl. Oakland

Sponsor: Johns Hopkins University

Sex: Male·Age: 13 - 21·Accepts healthy volunteers

Code: NCT06525064·Recruiting

Apply to this trial

Evaluation of the Efficacy, Safety, and Tolerability of LevoCept

for Contraception

27 locations incl. Berkeley

Sponsor: Sebela Women's Health Inc.

Sex: Female·Age: Up to 45·Accepts healthy volunteers

Code: NCT04457076·Phase 3·Not Yet Recruiting

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

for Left Ventricular Systolic Dysfunction

Drug: Finerenone

22 locations incl. Aurora

Sponsor: Bayer

Sex: All·Age: Up to 18

Code: NCT07192952·Phase 3·Recruiting

Apply to this trial

Pilot and Feasibility Study of Intra-articular Anti-CD14 for the Treatment of Knee Osteoarthritis

for Knee Osteoarthritis (Knee OA)

1 location in Philadelphia

Sponsor: VA Office of Research and Development

Sex: All·Age: 50 - 80

Code: NCT07481474·Phase 1·Not Yet Recruiting

First-in-human Study of a New Treatment (4A10) for Patients With Relapsed or Hard-to-treat Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma, Focused on Safety and How the Drug Behaves in the Body and Early Signs of Effect.

for Lymphoblastic Lymphoma

4 locations incl. Aurora

Sponsor: Allterum Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT07586618·Phase 1·Recruiting

Apply to this trial

Combined Functional Electrical and Transcranial Direct Current Stimulation for Foot Drop

for Falls

1 location in Philadelphia

Sponsor: Saint Joseph's University, Philadelphia

Sex: All·Age: 18+

Code: NCT07592221·Recruiting

Apply to this trial

Retreatment With CTL019/CTL119

for Lymphoma, B-Cell

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT04419909·Phase 1·Not Yet Recruiting

Efficacy and Safety of Novosis Putty in Transforaminal Lumbar Interbody Fusion for Patients With Lumbar Degenerative Disc Disease

for Degenerative Disc Disease

5 locations incl. Baton Rouge

Sponsor: CGBio Inc.

Sex: All·Age: 21 - 80

Code: NCT07017634·Phase 3·Recruiting

Apply to this trial