Clinical Trials at Hospital of the University of Pennsylvania

As of June 2026, 99 paid clinical trials are recruiting at Hospital of the University of Pennsylvania, located at 2121 MARKET ST APT 220, PHILADELPHIA, PA 19103-1309, phone (585) 235-7653 in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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99 clinical trials at Hospital of the University of Pennsylvania

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Multitracer [18F]Fluciclovine and 18F-FDG PET, and Advanced MRI for Metabolic Profiling of Glioblastoma

for Glioblastoma

2 locations incl. Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06613841·EARLY_Phase 1·Recruiting

Apply to this trial

T1D Pregnancy & Me

for Diabetes Mellitus, Type 1

10 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: Female·Age: 18+

Code: NCT06959316·Recruiting

Apply to this trial

Uterine Preservation in the Management of Placenta Accreta Spectrum Disorders

for Placenta Accreta Spectrum

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 18+

Code: NCT06512181·Recruiting

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Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

for Ventricular Tachycardia (VT)

6 locations incl. Boston

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18 - 85

Code: NCT06703489·Recruiting

Apply to this trial

Healing at Home 2.0 - Enhanced Chat Tool for Lowering Postpartum Depression

for Depression, Postpartum

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 18+

Code: NCT06877104·Recruiting

Apply to this trial

Videos to Aid Decision Making for Fibroid Treatment

for Uterine Bleeding

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 55

Code: NCT07072364·Recruiting

Apply to this trial

Prevail Global Study

for Coronary Artery Disease

51 locations incl. Birmingham

Sponsor: Medtronic Vascular

Sex: All·Age: 18+

Code: NCT06535854·Recruiting

Apply to this trial

A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

for Thrombocytopenia, Neonatal Alloimmune

Drug: Nipocalimab

12 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: Female·Age: 18 - 45

Code: NCT06533098·Phase 3·Recruiting

Apply to this trial

StrokeNet Thrombectomy Endovascular Platform

for Ischemic Stroke

41 locations incl. Birmingham

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06289985·Recruiting

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Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCL

for CTCL/ Mycosis Fungoides

17 locations incl. Phoenix

Sponsor: Soligenix

Sex: All·Age: 18+

Code: NCT06470451·Phase 3·Recruiting

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Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma

for Cutaneous Squamous Cell Carcinoma (CSCC)

Drug: Cemiplimab

45 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06585410·Phase 3·Recruiting

Apply to this trial

ViewFlex X ICE First-in-Human Study

for Cardiac Arrhythmias

8 locations incl. Jonesboro

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT06772493·Recruiting

Apply to this trial

The Neuralert Stroke Monitor Pilot Trial

for Stroke

1 location in Philadelphia

Sponsor: Neuralert Technologies LLC

Sex: All·Age: 22+

Code: NCT06368193·Recruiting

Apply to this trial

Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial

for Obstetrical Complications

14 locations incl. Birmingham

Sponsor: The George Washington University Biostatistics Center

Sex: Female·Age: All ages·Accepts healthy volunteers

Code: NCT06605118·Phase 3·Recruiting

Apply to this trial

The THOR IDE Study

for Peripheral Artery Disease

29 locations incl. St. Helena

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT05916950·Recruiting

Apply to this trial

Registry for Stage 2 Type 1 Diabetes

for Type 1 Diabetes

37 locations incl. Baltimore

Sponsor: Sanofi

Sex: All·Age: All ages

Code: NCT06481904·Recruiting

Apply to this trial

Postpartum Care in the NICU (PeliCaN) Transitions

for Stress Disorders, Post-Traumatic

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 16+

Code: NCT06521398·Recruiting

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An Intervention Mapping Approach to Closing the Gap in Maternal OUD and Infant NAS Care (SUPPORT)

for Opioid Use Disorder

3 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06576323·Recruiting

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AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy

for Mesial Temporal Lobe Epilepsy

18 locations incl. Birmingham

Sponsor: UniQure Biopharma B.V.

Sex: All·Age: 18 - 75

Code: NCT06063850·Phase 1, Phase 2·Recruiting

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Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

for Colorectal Cancer

32 locations incl. Chandler

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06445062·Phase 1, Phase 2·Recruiting

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Endovascular AAA Intervention Using the GORE® EXCLUDER® Conformable AAA Endoprosthesis or Iliac Branch Endoprosthesis

for AAA - Abdominal Aortic Aneurysm

56 locations incl. Little Rock

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06218875·Recruiting

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The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).

for Intracranial Aneurysm

22 locations incl. Englewood

Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All·Age: 18 - 75

Code: NCT02998229·Recruiting

Apply to this trial

iCare4Me Transitions

for Caregiver Stress

3 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06167746·Phase 3·Recruiting

Apply to this trial

Gram-Negative Bloodstream Infection Oral Antibiotic Therapy Trial

for Gram-negative Bacteremia

11 locations incl. San Francisco

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06080698·Recruiting

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A Study of Communication Between Clinicians, Patients, and Families in the Intensive Care Unit (ICU)

for Acute Respiratory Failure

5 locations incl. Chicago

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06042621·Enrolling By Invitation

BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

for Hypertension

70 locations incl. Scottsdale

Sponsor: Orchestra BioMed, Inc

Sex: All·Age: 18+

Code: NCT06059638·Recruiting

Apply to this trial

Zenith® Fenestrated+ Clinical Study

for Aortic Aneurysm, Abdominal

32 locations incl. Birmingham

Sponsor: Cook Research Incorporated

Sex: All·Age: 18+

Code: NCT04875429·Recruiting

Apply to this trial

Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders

for Delirium

7 locations incl. Orange

Sponsor: University of Michigan

Sex: All·Age: 70+

Code: NCT05929703·Recruiting

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Comparison of Apixaban Versus Enoxaparin

for Bladder Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06243510·Enrolling By Invitation

Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

for Progressive Pulmonary Fibrosis

70 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT05943535·Phase 3·Recruiting

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Nectero EAST System Clinical Study

for Abdominal Aortic Aneurysm

37 locations incl. Scottsdale

Sponsor: Nectero Medical, Inc.

Sex: All·Age: 21 - 85

Code: NCT06001918·Phase 2, Phase 3·Recruiting

Apply to this trial

CTSN Embolic Protection Trial

for Delirium

24 locations incl. North Little Rock

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 60+

Code: NCT06027788·Recruiting

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Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma

for Cholangiocarcinoma

Drug: Trametinib

10 locations incl. Los Angeles

Sponsor: Genfit

Sex: All·Age: 18+

Code: NCT05874414·Phase 1, Phase 2·Recruiting

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Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

for Hypertrophic Cardiomyopathy

10 locations incl. La Jolla

Sponsor: Tenaya Therapeutics

Sex: All·Age: 18 - 75

Code: NCT05836259·Phase 1, Phase 2·Recruiting

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A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

for Acute Myeloid Leukemia

Drug: Venetoclax

44 locations incl. Phoenix

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05735184·Phase 1·Recruiting

Apply to this trial

Randomized Assessment of TcMS for VT Storm

for Ventricular Tachycardia

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05599022·Recruiting

Apply to this trial

Prognostication of Recovery in Early Disorders of Consciousness Study

for Disorder of Consciousness

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07074678·Enrolling By Invitation

Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial

for Abdominal Aortic Aneurysm

32 locations incl. Loma Linda

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 20+

Code: NCT05378347·Recruiting

Apply to this trial

Continuation of the nuMoM2b Heart Health Study

for Cardiovascular Diseases

14 locations incl. Orange

Sponsor: RTI International

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT05472597·Enrolling By Invitation

Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease

for Idiopathic Pulmonary Fibrosis

86 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 40+

Code: NCT04905693·Phase 3·Enrolling By Invitation