Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,656 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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3,656 clinical trials

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HeartBeam ECG Registry

for Atrial Fibrillation

1 location in Pittsburgh

Sponsor: HeartBeam, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07501299·Not Yet Recruiting

Virtual Reality in End Stage Kidney Disease

for End Stage Kidney Disease

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages

Code: NCT06356168·Recruiting

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Phase II Study of Platinum/Etoposide Plus Ivonescimab for Extensive-Stage Small Cell Lung Cancer

for Extensive Stage Lung Small Cell Cancer

Drug: Ivonescimab

6 locations incl. New Brunswick

Sponsor: PrECOG, LLC.

Sex: All·Age: 18+

Code: NCT07057791·Phase 2·Recruiting

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Spinal Cord Stimulation for Children With Cerebral Palsy

for Cerebral Palsy

1 location in Pittsburgh

Sponsor: Martin Piazza

Sex: All·Age: 5 - 17·Accepts healthy volunteers

Code: NCT07516067·Recruiting

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Remimazolam NeuroImaging

for Anesthesia

1 location in Pittsburgh

Sponsor: Keith M Vogt

Sex: All·Age: 18 - 59·Accepts healthy volunteers

Code: NCT07290205·EARLY_Phase 1·Recruiting

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Streamlining Telehealth for Expanded PrEP Utilization Through Community Partnerships

for HIV

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 16+·Accepts healthy volunteers

Code: NCT07246057·Recruiting

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Neuralert Stroke Monitor Trial

for Surgery

1 location in Philadelphia

Sponsor: Neuralert Technologies LLC

Sex: All·Age: 22+

Code: NCT07362303·Recruiting

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Clinical Trial to Evaluate the Safety and Immunogenicity of the V2 Apex-Directed Immunogens DV201P-RNA and DV202B1-RNA in Adult Participants Without HIV

for HIV

7 locations incl. Atlanta

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07390474·Phase 1·Recruiting

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How Animal and Plant Protein Shakes Change the Body's Nutrient and Health Responses

for Cardiometabolic Health

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07121010·Recruiting

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Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

for Breast Neoplasms

39 locations incl. Birmingham

Sponsor: Natera, Inc.

Sex: All·Age: 18+

Code: NCT07214532·Recruiting

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A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

for Huntington Disease

9 locations incl. Englewood

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 21 - 70

Code: NCT07326709·Phase 3·Recruiting

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Kidney Transplant Improvement Through New Exercise Training to Increase Capacity

for Chronic Kidney Disease 5D

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 60+

Code: NCT07446296·Recruiting

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Little Cigar Oxidants

for Tobacco Use

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 21 - 65

Code: NCT06310187·Recruiting

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Enrichment of Glutathione Using Gamma-glutamylcysteine Supplementation in Parkinson's Disease Patients.

for Parkinsons Disease (PD)

1 location in Pittsburgh

Sponsor: Pravat Mandal

Sex: All·Age: 50 - 80

Code: NCT07064005·Phase 1·Recruiting

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Developing an Artificial Intelligence (AI) Chatbot for Adolescents and Young Adults With Eating Disorders

for Eating Disorders

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 12 - 26

Code: NCT07237607·Recruiting

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Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial

for Cardiovascular Disease

Drug: Olpasiran

6 locations incl. Bridgeport

Sponsor: Amgen

Sex: All·Age: 35 - 80

Code: NCT07293260·Phase 3·Recruiting

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PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease

for Proteinuric Kidney Diseases

25 locations incl. Huntsville

Sponsor: Boehringer Ingelheim

Sex: All·Age: 12+

Code: NCT07355296·Phase 2·Recruiting

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Application of Contrast-enhanced Ultrasound in Monitoring Soft Tissue Sarcoma Response to Neoadjuvant Radiotherapy

for Soft Tissue Sarcoma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07436364·EARLY_Phase 1·Recruiting

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First Time in Human (FTIH) Study to Investigate the Safety and Preliminary Activity of GSK5533524 Alone or in Combination in Adult Participants With Advanced Solid Tumors

for Neoplasms

2 locations incl. Philadelphia

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT07438782·Phase 1·Recruiting

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The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures

for Osteoporotic Fractures

2 locations incl. San Francisco

Sponsor: AO Foundation, AO Spine

Sex: All·Age: 50+

Code: NCT07027306·Recruiting

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A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1

for HIV

8 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07390955·Phase 1·Recruiting

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Pembrolizumab Plus Ultrasound-Induced Microbubble Cavitation in Head and Neck Cancer

for Head and Neck Cancer

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07501650·Phase 1·Recruiting

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A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT

for Adenovirus Infections

26 locations incl. Phoenix

Sponsor: SymBio Pharmaceuticals

Sex: All·Age: 2 Months+

Code: NCT07387367·Phase 3·Recruiting

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Feasibility of Intradialytic Monitoring During CKRT

for Acute Kidney Injury

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07428395·Enrolling By Invitation

Post Approval Effectiveness and Durability Evaluation of the Altaviva™ Tibial Device

for Urge Urinary Incontinence

5 locations incl. Homewood

Sponsor: MedtronicNeuro

Sex: All·Age: 18+

Code: NCT07456865·Recruiting

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The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial Aneurysms

for Hemorrhagic Stroke

17 locations incl. Phoenix

Sponsor: phenox Inc.

Sex: All·Age: 18+

Code: NCT07143019·Recruiting

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A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

for Obesity or Overweight

Drug: Enicepatide

25 locations incl. Anniston

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07351045·Phase 3·Recruiting

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A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)

for Idiopathic Hypersomnia

12 locations incl. Santa Monica

Sponsor: Harmony Biosciences Management, Inc.

Sex: All·Age: 18+

Code: NCT07500090·Phase 3·Recruiting

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Centering Autistic Perspectives in Behavioral Intervention Discussions

for Autism

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07165522·Not Yet Recruiting

Biomarker Feedback Intervention

for High Risk Drinking

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: 18 - 23·Accepts healthy volunteers

Code: NCT07307326·Not Yet Recruiting

A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.

for PROC

12 locations incl. Little Rock

Sponsor: Whitehawk Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07470853·Phase 1·Recruiting

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Endotype DIrected Treatment for OSA in Down Syndrome

for Obstructive Sleep Apnea (OSA)

5 locations incl. Tucson

Sponsor: University of Arizona

Sex: All·Age: 6+

Code: NCT07280468·Phase 4·Recruiting

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Flourish in Schools Pilot Study

for Psychological Distress

2 locations incl. Bay Village

Sponsor: Candice Biernesser

Sex: All·Age: 11 - 21

Code: NCT07506525·Recruiting

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A Study for CTC Expression and cfDNA/RNA Assessment in Metastatic Breast Cancer Patients

for Metastatic Breast Cancer (MBC)

1 location in Pittsburgh

Sponsor: Menarini Silicon Biosystems, INC

Sex: All·Age: 18+

Code: NCT06833853·Recruiting

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A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

for Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Drug: Nivolumab

34 locations incl. Phoenix

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07221149·Phase 2, Phase 3·Recruiting

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Supraglottic Airway for Resuscitation in Preemies

for Respiratory Failure

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 0 Days - 1 Day

Code: NCT07419438·Recruiting

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SPACE for Youth With Chronic Pain

for Chronic Pain

2 locations incl. Palo Alto

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10 - 17

Code: NCT07425691·Recruiting

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A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

for Non-Small Cell Lung Cancer (NSCLC)

Drug: Pumitamig

40 locations incl. Daphne

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07361510·Phase 3·Recruiting

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A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder

for Muscle-invasive Bladder Cancer

9 locations incl. Little Rock

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07475806·Phase 2·Recruiting

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A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic Amenorrhea

for Functional Hypothalamic Amenorrhea (FHA)

6 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18 - 40

Code: NCT07235917·Phase 2·Recruiting

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